STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CLPBClpB homolog, mitochondrial AAA ATPase chaperonin. (707 aa)    
Predicted Functional Partners:
CLPP
ATP-dependent Clp protease proteolytic subunit.
  
 
 0.998
GRPEL1
GrpE protein homolog; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the GrpE family.
  
 
 0.963
GRPEL2
GrpE protein homolog; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the GrpE family.
  
 
 0.961
HSPE1
Heat shock protein family E (Hsp10) member 1; Belongs to the GroES chaperonin family.
  
 
 0.950
HSPA9
Heat shock protein family A (Hsp70) member 9; Belongs to the heat shock protein 70 family.
  
 
 0.931
LONP1
Lon protease homolog, mitochondrial; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial promoters and RNA in a single-stranded, site-specific, and strand- specific manner. May regulate mi [...]
  
 
 0.912
LONP2
Lon protease homolog; Belongs to the peptidase S16 family.
  
 
 0.912
HSPA4
Heat shock protein family A (Hsp70) member 4.
  
 
 0.903
HSPA4L
Heat shock protein family A (Hsp70) member 4 like.
  
 
 0.901
HSPH1
Heat shock protein family H (Hsp110) member 1.
  
 
 0.901
Your Current Organism:
Myotis lucifugus
NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.