STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OSBPL8Oxysterol-binding protein; Belongs to the OSBP family. (863 aa)    
Predicted Functional Partners:
GPR89A
Uncharacterized protein.
 
      0.893
NPC1
NPC intracellular cholesterol transporter 1.
   
 0.799
NPC1L1
NPC1 like intracellular cholesterol transporter 1.
   
 0.799
ESYT2
Uncharacterized protein.
    
 
 0.792
IFRD2
Interferon related developmental regulator 2.
      
 0.763
MBLAC2
Metallo-beta-lactamase domain containing 2.
      
 0.760
NSDHL
NAD(P) dependent steroid dehydrogenase-like; Belongs to the 3-beta-HSD family.
     
 0.722
GFM2
Ribosome-releasing factor 2, mitochondrial; Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Acts in collaboration with MRRF. GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit. Not involved in the GTP-dependent ribosomal translocation step during translation elongation; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
      
 0.717
G1Q9I8_MYOLU
Uncharacterized protein.
      
 0.701
LDLRAP1
Low density lipoprotein receptor adaptor protein 1.
      
 0.685
Your Current Organism:
Myotis lucifugus
NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.