IL21R protein (Myotis lucifugus) - STRING interaction network

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Predicted Interactions

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Score

IL21R

Interleukin 21 receptor. (553 aa)

Predicted Functional Partners:

IL21

0.998

JAK1

0.974

IFNG

0.967

STAT3

0.962

IL6

0.960

IL4

0.957

IL10

0.952

G1P840_MYOLU

0.947

IL7

0.945

IL15

0.943

Your Current Organism:

Myotis lucifugus

NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
G1P840_MYOLU	IFNG	ENSMLUP00000006316	ENSMLUP00000002447	Fibronectin type-III domain-containing protein.	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.	0.946
G1P840_MYOLU	IL10	ENSMLUP00000006316	ENSMLUP00000016159	Fibronectin type-III domain-containing protein.	Interleukin 10.	0.917
G1P840_MYOLU	IL15	ENSMLUP00000006316	ENSMLUP00000006950	Fibronectin type-III domain-containing protein.	Interleukin; Belongs to the IL-15/IL-21 family.	0.997
G1P840_MYOLU	IL21	ENSMLUP00000006316	ENSMLUP00000009958	Fibronectin type-III domain-containing protein.	Interleukin; Belongs to the IL-15/IL-21 family.	0.948
G1P840_MYOLU	IL21R	ENSMLUP00000006316	ENSMLUP00000004634	Fibronectin type-III domain-containing protein.	Interleukin 21 receptor.	0.947
G1P840_MYOLU	IL4	ENSMLUP00000006316	ENSMLUP00000015107	Fibronectin type-III domain-containing protein.	Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Belongs to the IL-4/IL-13 family.	0.997
G1P840_MYOLU	IL6	ENSMLUP00000006316	ENSMLUP00000014444	Fibronectin type-III domain-containing protein.	Interleukin 6.	0.915
G1P840_MYOLU	IL7	ENSMLUP00000006316	ENSMLUP00000022178	Fibronectin type-III domain-containing protein.	Interleukin-7; Hematopoietic growth factor capable of stimulating the proliferation of lymphoid progenitors. It is important for proliferation during certain stages of B-cell maturation. Belongs to the IL-7/IL-9 family.	0.977
G1P840_MYOLU	JAK1	ENSMLUP00000006316	ENSMLUP00000007075	Fibronectin type-III domain-containing protein.	Tyrosine-protein kinase.	0.990
G1P840_MYOLU	STAT3	ENSMLUP00000006316	ENSMLUP00000015910	Fibronectin type-III domain-containing protein.	Signal transducer and activator of transcription.	0.902
IFNG	G1P840_MYOLU	ENSMLUP00000002447	ENSMLUP00000006316	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.	Fibronectin type-III domain-containing protein.	0.946
IFNG	IL10	ENSMLUP00000002447	ENSMLUP00000016159	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.	Interleukin 10.	0.962
IFNG	IL15	ENSMLUP00000002447	ENSMLUP00000006950	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.	Interleukin; Belongs to the IL-15/IL-21 family.	0.904
IFNG	IL21	ENSMLUP00000002447	ENSMLUP00000009958	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.	Interleukin; Belongs to the IL-15/IL-21 family.	0.786
IFNG	IL21R	ENSMLUP00000002447	ENSMLUP00000004634	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.	Interleukin 21 receptor.	0.967
IFNG	IL4	ENSMLUP00000002447	ENSMLUP00000015107	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.	Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Belongs to the IL-4/IL-13 family.	0.851
IFNG	IL6	ENSMLUP00000002447	ENSMLUP00000014444	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.	Interleukin 6.	0.933
IFNG	IL7	ENSMLUP00000002447	ENSMLUP00000022178	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.	Interleukin-7; Hematopoietic growth factor capable of stimulating the proliferation of lymphoid progenitors. It is important for proliferation during certain stages of B-cell maturation. Belongs to the IL-7/IL-9 family.	0.801
IFNG	JAK1	ENSMLUP00000002447	ENSMLUP00000007075	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.	Tyrosine-protein kinase.	0.967
IFNG	STAT3	ENSMLUP00000002447	ENSMLUP00000015910	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.	Signal transducer and activator of transcription.	0.899