CTCF protein (Myotis lucifugus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

CTCF

CCCTC-binding factor. (728 aa)

Predicted Functional Partners:

RAD21

0.920

STAG2

0.905

RAD21L1

0.857

EP300

0.800

STAG1

0.782

STAG3

0.771

G1PBB6_MYOLU

0.763

INO80D

0.742

NCOR1

0.741

SIN3A

0.695

Your Current Organism:

Myotis lucifugus

NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CTCF	EP300	ENSMLUP00000004761	ENSMLUP00000013493	CCCTC-binding factor.	E1A binding protein p300.	0.800
CTCF	G1PBB6_MYOLU	ENSMLUP00000004761	ENSMLUP00000007633	CCCTC-binding factor.	Uncharacterized protein.	0.763
CTCF	INO80D	ENSMLUP00000004761	ENSMLUP00000007053	CCCTC-binding factor.	INO80 complex subunit D.	0.742
CTCF	NCOR1	ENSMLUP00000004761	ENSMLUP00000001849	CCCTC-binding factor.	Nuclear receptor corepressor 1.	0.741
CTCF	RAD21	ENSMLUP00000004761	ENSMLUP00000005895	CCCTC-binding factor.	RAD21 cohesin complex component.	0.920
CTCF	RAD21L1	ENSMLUP00000004761	ENSMLUP00000021082	CCCTC-binding factor.	RAD21 cohesin complex component like 1.	0.857
CTCF	SIN3A	ENSMLUP00000004761	ENSMLUP00000008885	CCCTC-binding factor.	SIN3 transcription regulator family member A.	0.695
CTCF	STAG1	ENSMLUP00000004761	ENSMLUP00000009578	CCCTC-binding factor.	Stromal antigen 1.	0.782
CTCF	STAG2	ENSMLUP00000004761	ENSMLUP00000008553	CCCTC-binding factor.	Stromal antigen 2.	0.905
CTCF	STAG3	ENSMLUP00000004761	ENSMLUP00000015901	CCCTC-binding factor.	Stromal antigen 3.	0.771
EP300	CTCF	ENSMLUP00000013493	ENSMLUP00000004761	E1A binding protein p300.	CCCTC-binding factor.	0.800
EP300	NCOR1	ENSMLUP00000013493	ENSMLUP00000001849	E1A binding protein p300.	Nuclear receptor corepressor 1.	0.938
EP300	RAD21	ENSMLUP00000013493	ENSMLUP00000005895	E1A binding protein p300.	RAD21 cohesin complex component.	0.410
EP300	SIN3A	ENSMLUP00000013493	ENSMLUP00000008885	E1A binding protein p300.	SIN3 transcription regulator family member A.	0.713
EP300	STAG2	ENSMLUP00000013493	ENSMLUP00000008553	E1A binding protein p300.	Stromal antigen 2.	0.665
G1PBB6_MYOLU	CTCF	ENSMLUP00000007633	ENSMLUP00000004761	Uncharacterized protein.	CCCTC-binding factor.	0.763
INO80D	CTCF	ENSMLUP00000007053	ENSMLUP00000004761	INO80 complex subunit D.	CCCTC-binding factor.	0.742
NCOR1	CTCF	ENSMLUP00000001849	ENSMLUP00000004761	Nuclear receptor corepressor 1.	CCCTC-binding factor.	0.741
NCOR1	EP300	ENSMLUP00000001849	ENSMLUP00000013493	Nuclear receptor corepressor 1.	E1A binding protein p300.	0.938
NCOR1	SIN3A	ENSMLUP00000001849	ENSMLUP00000008885	Nuclear receptor corepressor 1.	SIN3 transcription regulator family member A.	0.982