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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HMGCL3-hydroxy-3-methylglutaryl-CoA lyase. (327 aa)    
Predicted Functional Partners:
BCAT1
Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
  
 0.983
ACAT1
Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.969
HMGCS2
3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.
    
 0.968
BDH1
3-hydroxybutyrate dehydrogenase 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
     
 0.966
G1NZH5_MYOLU
Uncharacterized protein.
  
 
 0.963
HADHB
Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.958
IDH3G
Isocitrate dehydrogenase [NAD] subunit, mitochondrial.
  
 0.950
IDH3B
Isocitrate dehydrogenase [NAD] subunit, mitochondrial.
  
 0.950
IDH3A
Isocitrate dehydrogenase [NAD] subunit, mitochondrial.
  
 0.950
G1QDT0_MYOLU
Iso_dh domain-containing protein.
  
 0.950
Your Current Organism:
Myotis lucifugus
NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat
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