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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HLA-DMAMajor histocompatibility complex, class II, DM alpha; Belongs to the MHC class II family. (252 aa)    
Predicted Functional Partners:
LOC102421254
Ig-like domain-containing protein.
 
 
0.999
LOC102418131
Ig-like domain-containing protein; Belongs to the MHC class II family.
   
0.999
LOC102443188
Uncharacterized protein; Belongs to the MHC class II family.
  
0.998
G1QBV7_MYOLU
Ig-like domain-containing protein; Belongs to the MHC class II family.
   
0.997
G1Q9G7_MYOLU
Ig-like domain-containing protein; Belongs to the MHC class II family.
  
0.991
CD74
CD74 molecule.
   
 0.991
LOC102441293
Ig-like domain-containing protein; Belongs to the MHC class II family.
  
0.988
LOC102416953
Ig-like domain-containing protein; Belongs to the MHC class II family.
  
0.986
LOC102419180
Ig-like domain-containing protein; Belongs to the MHC class II family.
  
0.986
HLA-DPB1
Major histocompatibility complex, class II, DP beta 1.
   
 0.974
Your Current Organism:
Myotis lucifugus
NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.