GATA2 protein (Myotis lucifugus) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

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[Homology]

Score

GATA2

GATA binding protein 2. (480 aa)

Predicted Functional Partners:

TAL1

0.945

RUNX1

0.917

LMO2

0.911

G1QGE1_MYOLU

0.891

LDB1

0.870

FOXA1

0.855

LDB2

0.848

FOXA2

0.844

TBX21

0.827

EP300

0.806

Your Current Organism:

Myotis lucifugus

NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EP300	FOXA1	ENSMLUP00000013493	ENSMLUP00000020719	E1A binding protein p300.	Forkhead box A1.	0.965
EP300	FOXA2	ENSMLUP00000013493	ENSMLUP00000017813	E1A binding protein p300.	Forkhead box A2.	0.743
EP300	G1QGE1_MYOLU	ENSMLUP00000013493	ENSMLUP00000022774	E1A binding protein p300.	Uncharacterized protein.	0.679
EP300	GATA2	ENSMLUP00000013493	ENSMLUP00000005028	E1A binding protein p300.	GATA binding protein 2.	0.806
EP300	RUNX1	ENSMLUP00000013493	ENSMLUP00000005300	E1A binding protein p300.	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	0.793
EP300	TAL1	ENSMLUP00000013493	ENSMLUP00000005835	E1A binding protein p300.	TAL bHLH transcription factor 1, erythroid differentiation factor.	0.689
FOXA1	EP300	ENSMLUP00000020719	ENSMLUP00000013493	Forkhead box A1.	E1A binding protein p300.	0.965
FOXA1	FOXA2	ENSMLUP00000020719	ENSMLUP00000017813	Forkhead box A1.	Forkhead box A2.	0.574
FOXA1	GATA2	ENSMLUP00000020719	ENSMLUP00000005028	Forkhead box A1.	GATA binding protein 2.	0.855
FOXA2	EP300	ENSMLUP00000017813	ENSMLUP00000013493	Forkhead box A2.	E1A binding protein p300.	0.743
FOXA2	FOXA1	ENSMLUP00000017813	ENSMLUP00000020719	Forkhead box A2.	Forkhead box A1.	0.574
FOXA2	GATA2	ENSMLUP00000017813	ENSMLUP00000005028	Forkhead box A2.	GATA binding protein 2.	0.844
FOXA2	TAL1	ENSMLUP00000017813	ENSMLUP00000005835	Forkhead box A2.	TAL bHLH transcription factor 1, erythroid differentiation factor.	0.465
G1QGE1_MYOLU	EP300	ENSMLUP00000022774	ENSMLUP00000013493	Uncharacterized protein.	E1A binding protein p300.	0.679
G1QGE1_MYOLU	GATA2	ENSMLUP00000022774	ENSMLUP00000005028	Uncharacterized protein.	GATA binding protein 2.	0.891
G1QGE1_MYOLU	LDB1	ENSMLUP00000022774	ENSMLUP00000008417	Uncharacterized protein.	LIM domain binding 1.	0.566
G1QGE1_MYOLU	LDB2	ENSMLUP00000022774	ENSMLUP00000002450	Uncharacterized protein.	LIM domain binding 2.	0.548
G1QGE1_MYOLU	LMO2	ENSMLUP00000022774	ENSMLUP00000003354	Uncharacterized protein.	LIM domain only 2.	0.555
G1QGE1_MYOLU	RUNX1	ENSMLUP00000022774	ENSMLUP00000005300	Uncharacterized protein.	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	0.714
G1QGE1_MYOLU	TAL1	ENSMLUP00000022774	ENSMLUP00000005835	Uncharacterized protein.	TAL bHLH transcription factor 1, erythroid differentiation factor.	0.534