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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EME1Essential meiotic structure-specific endonuclease 1. (573 aa)    
Predicted Functional Partners:
MUS81
MUS81 structure-specific endonuclease subunit.
   
 0.999
SLX4
SLX4 structure-specific endonuclease subunit.
    
 0.979
EME2
Essential meiotic structure-specific endonuclease subunit 2.
  
  
0.954
SLX1
Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. Has a preference for 5'-flap structures, and promotes symmetrical cleavage of static and migrating Holliday junctions (HJs). Resolves HJs by generating two pairs of ligatable, nicked duplex products.
    
 0.917
ERCC1
ERCC excision repair 1, endonuclease non-catalytic subunit.
    
 0.910
GEN1
GEN1 Holliday junction 5' flap endonuclease.
   
 0.904
NARS1
Asparaginyl-tRNA synthetase.
    
 0.898
L7N119_MYOLU
Uncharacterized protein.
   
 0.888
LOC102429896
XPGI domain-containing protein.
   
 0.888
FANCE
FA complementation group E.
    
 0.874
Your Current Organism:
Myotis lucifugus
NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat
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