| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KDM1A | NCOR1 | ENSMLUP00000009662 | ENSMLUP00000001849 | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. | Nuclear receptor corepressor 1. | 0.472 |
| KDM1A | NR2E1 | ENSMLUP00000009662 | ENSMLUP00000005064 | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. | Nuclear receptor subfamily 2 group E member 1. | 0.759 |
| LOC102431112 | NR2E1 | ENSMLUP00000016838 | ENSMLUP00000005064 | Uncharacterized protein. | Nuclear receptor subfamily 2 group E member 1. | 0.936 |
| LOC102431112 | RERE | ENSMLUP00000016838 | ENSMLUP00000004278 | Uncharacterized protein. | Arginine-glutamic acid dipeptide repeats. | 0.590 |
| MED1 | NCOA3 | ENSMLUP00000006061 | ENSMLUP00000000383 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | Nuclear receptor coactivator. | 0.920 |
| MED1 | NCOR1 | ENSMLUP00000006061 | ENSMLUP00000001849 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | Nuclear receptor corepressor 1. | 0.767 |
| MED1 | NR2E1 | ENSMLUP00000006061 | ENSMLUP00000005064 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | Nuclear receptor subfamily 2 group E member 1. | 0.764 |
| MED1 | SMARCD2 | ENSMLUP00000006061 | ENSMLUP00000010681 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2. | 0.561 |
| MED1 | TADA1 | ENSMLUP00000006061 | ENSMLUP00000003725 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | Transcriptional adaptor 1. | 0.698 |
| NCOA3 | MED1 | ENSMLUP00000000383 | ENSMLUP00000006061 | Nuclear receptor coactivator. | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | 0.920 |
| NCOA3 | NCOR1 | ENSMLUP00000000383 | ENSMLUP00000001849 | Nuclear receptor coactivator. | Nuclear receptor corepressor 1. | 0.816 |
| NCOA3 | NR2E1 | ENSMLUP00000000383 | ENSMLUP00000005064 | Nuclear receptor coactivator. | Nuclear receptor subfamily 2 group E member 1. | 0.746 |
| NCOA3 | SMARCD2 | ENSMLUP00000000383 | ENSMLUP00000010681 | Nuclear receptor coactivator. | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2. | 0.561 |
| NCOA3 | TADA1 | ENSMLUP00000000383 | ENSMLUP00000003725 | Nuclear receptor coactivator. | Transcriptional adaptor 1. | 0.672 |
| NCOR1 | KDM1A | ENSMLUP00000001849 | ENSMLUP00000009662 | Nuclear receptor corepressor 1. | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. | 0.472 |
| NCOR1 | MED1 | ENSMLUP00000001849 | ENSMLUP00000006061 | Nuclear receptor corepressor 1. | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | 0.767 |
| NCOR1 | NCOA3 | ENSMLUP00000001849 | ENSMLUP00000000383 | Nuclear receptor corepressor 1. | Nuclear receptor coactivator. | 0.816 |
| NCOR1 | NR2E1 | ENSMLUP00000001849 | ENSMLUP00000005064 | Nuclear receptor corepressor 1. | Nuclear receptor subfamily 2 group E member 1. | 0.805 |
| NCOR1 | RERE | ENSMLUP00000001849 | ENSMLUP00000004278 | Nuclear receptor corepressor 1. | Arginine-glutamic acid dipeptide repeats. | 0.452 |
| NCOR1 | SMARCD2 | ENSMLUP00000001849 | ENSMLUP00000010681 | Nuclear receptor corepressor 1. | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2. | 0.759 |