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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MAP3K14Mitogen-activated protein kinase kinase kinase 14. (957 aa)    
Predicted Functional Partners:
TRAF3
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.998
CHUK
Component of inhibitor of nuclear factor kappa B kinase complex.
   
0.997
IKBKG
Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma.
    
 0.981
TRAF6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.974
TRAF5
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.973
IKBKB
Uncharacterized protein.
   
0.972
LOC102430620
Uncharacterized protein.
   
 0.972
MAP3K8
Mitogen-activated protein kinase kinase kinase 8.
    
0.968
TRAF1
TNF receptor-associated factor.
    
 0.953
MAP3K7
Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
    
0.923
Your Current Organism:
Myotis lucifugus
NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.