PRDX1 protein (Myotis lucifugus) - STRING interaction network

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PRDX1

Peroxiredoxin-1; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2) (By similarity). Reduces an intramolecular disulfide bond in GDPD5 that gates the ability to GDPD5 to drive postmitotic motor neuron diffe [...] (199 aa)

Predicted Functional Partners:

SRXN1

0.996

TXN

0.961

G1PPB7_MYOLU

0.947

NME8

0.946

G1P9S4_MYOLU

0.939

PRDX5

0.933

G1Q1S1_MYOLU

0.933

TXN2

0.918

G1PK52_MYOLU

0.861

CAT

0.859

Your Current Organism:

Myotis lucifugus

NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CAT	G1P9S4_MYOLU	ENSMLUP00000002441	ENSMLUP00000006993	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.	Thioredoxin domain-containing protein.	0.439
CAT	G1PK52_MYOLU	ENSMLUP00000002441	ENSMLUP00000011153	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.	0.953
CAT	G1PPB7_MYOLU	ENSMLUP00000002441	ENSMLUP00000012842	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.	Thioredoxin domain-containing protein.	0.439
CAT	G1Q1S1_MYOLU	ENSMLUP00000002441	ENSMLUP00000017654	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.	Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.	0.533
CAT	NME8	ENSMLUP00000002441	ENSMLUP00000003816	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.	NME/NM23 family member 8.	0.698
CAT	PRDX1	ENSMLUP00000002441	ENSMLUP00000005182	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.	Peroxiredoxin-1; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2) (By similarity). Reduces an intramolecular disulfide bond in GDPD5 that gates the ability to GDPD5 to drive postmitotic motor neuron diffe [...]	0.859
CAT	PRDX5	ENSMLUP00000002441	ENSMLUP00000008059	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.	Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.	0.533
CAT	SRXN1	ENSMLUP00000002441	ENSMLUP00000021109	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.	Sulfiredoxin.	0.484
CAT	TXN	ENSMLUP00000002441	ENSMLUP00000008255	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.	Thioredoxin; Belongs to the thioredoxin family.	0.439
CAT	TXN2	ENSMLUP00000002441	ENSMLUP00000014428	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.	Thioredoxin 2.	0.467
G1P9S4_MYOLU	CAT	ENSMLUP00000006993	ENSMLUP00000002441	Thioredoxin domain-containing protein.	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.	0.439
G1P9S4_MYOLU	G1PK52_MYOLU	ENSMLUP00000006993	ENSMLUP00000011153	Thioredoxin domain-containing protein.	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.	0.469
G1P9S4_MYOLU	G1PPB7_MYOLU	ENSMLUP00000006993	ENSMLUP00000012842	Thioredoxin domain-containing protein.	Thioredoxin domain-containing protein.	0.633
G1P9S4_MYOLU	G1Q1S1_MYOLU	ENSMLUP00000006993	ENSMLUP00000017654	Thioredoxin domain-containing protein.	Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.	0.905
G1P9S4_MYOLU	NME8	ENSMLUP00000006993	ENSMLUP00000003816	Thioredoxin domain-containing protein.	NME/NM23 family member 8.	0.511
G1P9S4_MYOLU	PRDX1	ENSMLUP00000006993	ENSMLUP00000005182	Thioredoxin domain-containing protein.	Peroxiredoxin-1; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2) (By similarity). Reduces an intramolecular disulfide bond in GDPD5 that gates the ability to GDPD5 to drive postmitotic motor neuron diffe [...]	0.939
G1P9S4_MYOLU	PRDX5	ENSMLUP00000006993	ENSMLUP00000008059	Thioredoxin domain-containing protein.	Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.	0.905
G1P9S4_MYOLU	SRXN1	ENSMLUP00000006993	ENSMLUP00000021109	Thioredoxin domain-containing protein.	Sulfiredoxin.	0.442
G1P9S4_MYOLU	TXN2	ENSMLUP00000006993	ENSMLUP00000014428	Thioredoxin domain-containing protein.	Thioredoxin 2.	0.908
G1PK52_MYOLU	CAT	ENSMLUP00000011153	ENSMLUP00000002441	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.	0.953

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