Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
WFDC8WAP four-disulfide core domain 8. (231 aa)    
Predicted Functional Partners:
SPINT4
Serine peptidase inhibitor, Kunitz type 4.
      
 0.722
ATP4B
Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.
   
  
 0.692
GLB1L
Galactosidase beta 1 like; Belongs to the glycosyl hydrolase 35 family.
      
 0.657
F13B
Coagulation factor XIII B chain.
   
  
 0.592
SPINT2
Serine peptidase inhibitor, Kunitz type 2.
      
 0.585
VPS18
VPS18 core subunit of CORVET and HOPS complexes.
      
 0.584
F12
Coagulation factor XII.
    
 0.569
TEX101
Testis expressed 101.
   
  
 0.558
MPG
N-methylpurine DNA glycosylase.
      
 0.539
MAT2B
Methionine adenosyltransferase 2 subunit beta; Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine.
   
  
 0.539
Your Current Organism:
Myotis lucifugus
NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat
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