CD40 protein (Myotis lucifugus) - STRING interaction network

Nodes:

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Gene Fusion

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Coexpression

Experiments

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[Homology]

Score

CD40

CD40 molecule. (291 aa)

Predicted Functional Partners:

CD40LG

0.998

TRAF6

0.983

TRAF3

0.981

TRAF5

0.963

TRAF1

0.949

TNF

0.922

TNFSF18

0.907

G1PJ64_MYOLU

0.901

CD86

0.891

BTLA

0.887

Your Current Organism:

Myotis lucifugus

NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BTLA	CD40	ENSMLUP00000001442	ENSMLUP00000005488	B and T lymphocyte associated.	CD40 molecule.	0.887
BTLA	CD40LG	ENSMLUP00000001442	ENSMLUP00000007096	B and T lymphocyte associated.	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.	0.508
BTLA	CD86	ENSMLUP00000001442	ENSMLUP00000013974	B and T lymphocyte associated.	CD86 molecule.	0.513
BTLA	G1PJ64_MYOLU	ENSMLUP00000001442	ENSMLUP00000010780	B and T lymphocyte associated.	Uncharacterized protein.	0.666
BTLA	TNF	ENSMLUP00000001442	ENSMLUP00000003613	B and T lymphocyte associated.	Tumor necrosis factor; Belongs to the tumor necrosis factor family.	0.418
CD40	BTLA	ENSMLUP00000005488	ENSMLUP00000001442	CD40 molecule.	B and T lymphocyte associated.	0.887
CD40	CD40LG	ENSMLUP00000005488	ENSMLUP00000007096	CD40 molecule.	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.	0.998
CD40	CD86	ENSMLUP00000005488	ENSMLUP00000013974	CD40 molecule.	CD86 molecule.	0.891
CD40	G1PJ64_MYOLU	ENSMLUP00000005488	ENSMLUP00000010780	CD40 molecule.	Uncharacterized protein.	0.901
CD40	TNF	ENSMLUP00000005488	ENSMLUP00000003613	CD40 molecule.	Tumor necrosis factor; Belongs to the tumor necrosis factor family.	0.922
CD40	TNFSF18	ENSMLUP00000005488	ENSMLUP00000016209	CD40 molecule.	Tumor necrosis factor ligand 2A.	0.907
CD40	TRAF1	ENSMLUP00000005488	ENSMLUP00000004594	CD40 molecule.	TNF receptor-associated factor.	0.949
CD40	TRAF3	ENSMLUP00000005488	ENSMLUP00000008817	CD40 molecule.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.981
CD40	TRAF5	ENSMLUP00000005488	ENSMLUP00000017777	CD40 molecule.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.963
CD40	TRAF6	ENSMLUP00000005488	ENSMLUP00000003284	CD40 molecule.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.983
CD40LG	BTLA	ENSMLUP00000007096	ENSMLUP00000001442	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.	B and T lymphocyte associated.	0.508
CD40LG	CD40	ENSMLUP00000007096	ENSMLUP00000005488	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.	CD40 molecule.	0.998
CD40LG	CD86	ENSMLUP00000007096	ENSMLUP00000013974	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.	CD86 molecule.	0.968
CD40LG	G1PJ64_MYOLU	ENSMLUP00000007096	ENSMLUP00000010780	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.	Uncharacterized protein.	0.804
CD40LG	TNF	ENSMLUP00000007096	ENSMLUP00000003613	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.	Tumor necrosis factor; Belongs to the tumor necrosis factor family.	0.876