CISD2 protein (Myotis lucifugus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

CISD2

CDGSH iron sulfur domain 2. (135 aa)

Predicted Functional Partners:

TIMM10

0.978

SDHD

0.920

G1P7R8_MYOLU

0.913

L7N1V1_MYOLU

0.913

TIMM10B

0.913

G1Q7B8_MYOLU

0.913

LOC102422306

0.880

SLU7

0.845

NDUFA8

0.836

PRKRIP1

0.831

Your Current Organism:

Myotis lucifugus

NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CISD2	G1P7R8_MYOLU	ENSMLUP00000005494	ENSMLUP00000006180	CDGSH iron sulfur domain 2.	zf-Tim10_DDP domain-containing protein.	0.913
CISD2	G1Q7B8_MYOLU	ENSMLUP00000005494	ENSMLUP00000019601	CDGSH iron sulfur domain 2.	Ig-like domain-containing protein.	0.913
CISD2	L7N1V1_MYOLU	ENSMLUP00000005494	ENSMLUP00000015374	CDGSH iron sulfur domain 2.	Ig-like domain-containing protein.	0.913
CISD2	LOC102422306	ENSMLUP00000005494	ENSMLUP00000000562	CDGSH iron sulfur domain 2.	Mitochondrial import inner membrane translocase subunit TIM23; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.	0.880
CISD2	NDUFA8	ENSMLUP00000005494	ENSMLUP00000004346	CDGSH iron sulfur domain 2.	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.	0.836
CISD2	PRKRIP1	ENSMLUP00000005494	ENSMLUP00000005554	CDGSH iron sulfur domain 2.	PRKR interacting protein 1.	0.831
CISD2	SDHD	ENSMLUP00000005494	ENSMLUP00000011142	CDGSH iron sulfur domain 2.	Succinate dehydrogenase [ubiquinone] cytochrome b small subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q); Belongs to the CybS family.	0.920
CISD2	SLU7	ENSMLUP00000005494	ENSMLUP00000002811	CDGSH iron sulfur domain 2.	SLU7 homolog, splicing factor.	0.845
CISD2	TIMM10	ENSMLUP00000005494	ENSMLUP00000007182	CDGSH iron sulfur domain 2.	Translocase of inner mitochondrial membrane 10.	0.978
CISD2	TIMM10B	ENSMLUP00000005494	ENSMLUP00000015754	CDGSH iron sulfur domain 2.	zf-Tim10_DDP domain-containing protein.	0.913
G1P7R8_MYOLU	CISD2	ENSMLUP00000006180	ENSMLUP00000005494	zf-Tim10_DDP domain-containing protein.	CDGSH iron sulfur domain 2.	0.913
G1P7R8_MYOLU	LOC102422306	ENSMLUP00000006180	ENSMLUP00000000562	zf-Tim10_DDP domain-containing protein.	Mitochondrial import inner membrane translocase subunit TIM23; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.	0.929
G1P7R8_MYOLU	SDHD	ENSMLUP00000006180	ENSMLUP00000011142	zf-Tim10_DDP domain-containing protein.	Succinate dehydrogenase [ubiquinone] cytochrome b small subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q); Belongs to the CybS family.	0.789
G1P7R8_MYOLU	TIMM10	ENSMLUP00000006180	ENSMLUP00000007182	zf-Tim10_DDP domain-containing protein.	Translocase of inner mitochondrial membrane 10.	0.999
G1P7R8_MYOLU	TIMM10B	ENSMLUP00000006180	ENSMLUP00000015754	zf-Tim10_DDP domain-containing protein.	zf-Tim10_DDP domain-containing protein.	0.998
G1Q7B8_MYOLU	CISD2	ENSMLUP00000019601	ENSMLUP00000005494	Ig-like domain-containing protein.	CDGSH iron sulfur domain 2.	0.913
G1Q7B8_MYOLU	LOC102422306	ENSMLUP00000019601	ENSMLUP00000000562	Ig-like domain-containing protein.	Mitochondrial import inner membrane translocase subunit TIM23; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.	0.847
G1Q7B8_MYOLU	SDHD	ENSMLUP00000019601	ENSMLUP00000011142	Ig-like domain-containing protein.	Succinate dehydrogenase [ubiquinone] cytochrome b small subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q); Belongs to the CybS family.	0.768
G1Q7B8_MYOLU	TIMM10	ENSMLUP00000019601	ENSMLUP00000007182	Ig-like domain-containing protein.	Translocase of inner mitochondrial membrane 10.	0.993
L7N1V1_MYOLU	CISD2	ENSMLUP00000015374	ENSMLUP00000005494	Ig-like domain-containing protein.	CDGSH iron sulfur domain 2.	0.913