STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MPOMyeloperoxidase. (728 aa)    
Predicted Functional Partners:
RUNX1
Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.
   
 
 0.869
CES5A
Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.
    
 0.867
GOT1
Aspartate aminotransferase.
    
 0.863
PRTN3
Proteinase 3; Belongs to the peptidase S1 family.
   
 
 0.834
ELANE
Elastase, neutrophil expressed; Belongs to the peptidase S1 family.
   
 
 0.818
G1NW29_MYOLU
Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.
    
 0.802
G1PY65_MYOLU
Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.
    
 0.802
LOC102417797
Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.
    
 0.802
GOT2
Aspartate aminotransferase.
    
 0.777
ENSMLUP00000021834
annotation not available
    
 0.777
Your Current Organism:
Myotis lucifugus
NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.