L7N1A2_MYOLU protein (Myotis lucifugus) - STRING interaction network

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Score

L7N1A2_MYOLU

Uncharacterized protein. (775 aa)

Predicted Functional Partners:

PARG

0.861

XPC

0.752

FEN1

0.735

WDR76

0.713

DDB2

0.713

BRCA2

0.706

XRCC5

0.705

XRCC6

0.680

UBE2I

0.670

KCTD2

0.670

Your Current Organism:

Myotis lucifugus

NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BRCA2	FEN1	ENSMLUP00000012516	ENSMLUP00000009461	BRCA2 DNA repair associated.	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	0.816
BRCA2	L7N1A2_MYOLU	ENSMLUP00000012516	ENSMLUP00000005619	BRCA2 DNA repair associated.	Uncharacterized protein.	0.706
BRCA2	PARG	ENSMLUP00000012516	ENSMLUP00000001594	BRCA2 DNA repair associated.	Poly(ADP-ribose) glycohydrolase.	0.573
BRCA2	XPC	ENSMLUP00000012516	ENSMLUP00000009722	BRCA2 DNA repair associated.	XPC complex subunit, DNA damage recognition and repair factor.	0.496
BRCA2	XRCC5	ENSMLUP00000012516	ENSMLUP00000012440	BRCA2 DNA repair associated.	X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family.	0.653
BRCA2	XRCC6	ENSMLUP00000012516	ENSMLUP00000002285	BRCA2 DNA repair associated.	X-ray repair cross complementing 6.	0.646
DDB2	FEN1	ENSMLUP00000016091	ENSMLUP00000009461	Damage specific DNA binding protein 2.	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	0.826
DDB2	KCTD2	ENSMLUP00000016091	ENSMLUP00000011683	Damage specific DNA binding protein 2.	Potassium channel tetramerization domain containing 2.	0.627
DDB2	L7N1A2_MYOLU	ENSMLUP00000016091	ENSMLUP00000005619	Damage specific DNA binding protein 2.	Uncharacterized protein.	0.713
DDB2	PARG	ENSMLUP00000016091	ENSMLUP00000001594	Damage specific DNA binding protein 2.	Poly(ADP-ribose) glycohydrolase.	0.414
DDB2	UBE2I	ENSMLUP00000016091	ENSMLUP00000007507	Damage specific DNA binding protein 2.	Ubiquitin conjugating enzyme E2 I; Belongs to the ubiquitin-conjugating enzyme family.	0.677
DDB2	XPC	ENSMLUP00000016091	ENSMLUP00000009722	Damage specific DNA binding protein 2.	XPC complex subunit, DNA damage recognition and repair factor.	0.966
DDB2	XRCC5	ENSMLUP00000016091	ENSMLUP00000012440	Damage specific DNA binding protein 2.	X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family.	0.652
DDB2	XRCC6	ENSMLUP00000016091	ENSMLUP00000002285	Damage specific DNA binding protein 2.	X-ray repair cross complementing 6.	0.653
FEN1	BRCA2	ENSMLUP00000009461	ENSMLUP00000012516	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	BRCA2 DNA repair associated.	0.816
FEN1	DDB2	ENSMLUP00000009461	ENSMLUP00000016091	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	Damage specific DNA binding protein 2.	0.826
FEN1	L7N1A2_MYOLU	ENSMLUP00000009461	ENSMLUP00000005619	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	Uncharacterized protein.	0.735
FEN1	PARG	ENSMLUP00000009461	ENSMLUP00000001594	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	Poly(ADP-ribose) glycohydrolase.	0.742
FEN1	WDR76	ENSMLUP00000009461	ENSMLUP00000004354	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	WD repeat-containing protein 76; Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC. Belongs to the WD repeat DDB2/WDR76 family.	0.875
FEN1	XPC	ENSMLUP00000009461	ENSMLUP00000009722	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	XPC complex subunit, DNA damage recognition and repair factor.	0.765