UNC13B protein (Myotis lucifugus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

UNC13B

Unc-13 homolog B. (1628 aa)

Predicted Functional Partners:

RIMS2

0.999

RIMS1

0.985

TSPOAP1

0.973

UNC13C

0.874

UNC13A

0.874

CASK

0.869

RIMS3

0.865

LIN7C

0.859

SNAP25

0.838

RIMS4

0.837

Your Current Organism:

Myotis lucifugus

NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CASK	LIN7C	ENSMLUP00000002731	ENSMLUP00000014508	Calcium/calmodulin dependent serine protein kinase; Belongs to the MAGUK family.	Protein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family.	0.998
CASK	RIMS1	ENSMLUP00000002731	ENSMLUP00000021789	Calcium/calmodulin dependent serine protein kinase; Belongs to the MAGUK family.	Regulating synaptic membrane exocytosis 1.	0.878
CASK	RIMS2	ENSMLUP00000002731	ENSMLUP00000006688	Calcium/calmodulin dependent serine protein kinase; Belongs to the MAGUK family.	Regulating synaptic membrane exocytosis 2.	0.967
CASK	RIMS3	ENSMLUP00000002731	ENSMLUP00000006572	Calcium/calmodulin dependent serine protein kinase; Belongs to the MAGUK family.	Regulating synaptic membrane exocytosis 3.	0.885
CASK	RIMS4	ENSMLUP00000002731	ENSMLUP00000014755	Calcium/calmodulin dependent serine protein kinase; Belongs to the MAGUK family.	Regulating synaptic membrane exocytosis 4.	0.735
CASK	SNAP25	ENSMLUP00000002731	ENSMLUP00000006584	Calcium/calmodulin dependent serine protein kinase; Belongs to the MAGUK family.	Synaptosomal-associated protein; Belongs to the SNAP-25 family.	0.765
CASK	TSPOAP1	ENSMLUP00000002731	ENSMLUP00000005582	Calcium/calmodulin dependent serine protein kinase; Belongs to the MAGUK family.	TSPO associated protein 1.	0.834
CASK	UNC13A	ENSMLUP00000002731	ENSMLUP00000019833	Calcium/calmodulin dependent serine protein kinase; Belongs to the MAGUK family.	Uncharacterized protein.	0.869
CASK	UNC13B	ENSMLUP00000002731	ENSMLUP00000005661	Calcium/calmodulin dependent serine protein kinase; Belongs to the MAGUK family.	Unc-13 homolog B.	0.869
CASK	UNC13C	ENSMLUP00000002731	ENSMLUP00000002426	Calcium/calmodulin dependent serine protein kinase; Belongs to the MAGUK family.	Unc-13 homolog C.	0.869
LIN7C	CASK	ENSMLUP00000014508	ENSMLUP00000002731	Protein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family.	Calcium/calmodulin dependent serine protein kinase; Belongs to the MAGUK family.	0.998
LIN7C	RIMS1	ENSMLUP00000014508	ENSMLUP00000021789	Protein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family.	Regulating synaptic membrane exocytosis 1.	0.575
LIN7C	RIMS2	ENSMLUP00000014508	ENSMLUP00000006688	Protein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family.	Regulating synaptic membrane exocytosis 2.	0.681
LIN7C	RIMS4	ENSMLUP00000014508	ENSMLUP00000014755	Protein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family.	Regulating synaptic membrane exocytosis 4.	0.635
LIN7C	SNAP25	ENSMLUP00000014508	ENSMLUP00000006584	Protein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family.	Synaptosomal-associated protein; Belongs to the SNAP-25 family.	0.630
LIN7C	TSPOAP1	ENSMLUP00000014508	ENSMLUP00000005582	Protein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family.	TSPO associated protein 1.	0.639
LIN7C	UNC13A	ENSMLUP00000014508	ENSMLUP00000019833	Protein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family.	Uncharacterized protein.	0.575
LIN7C	UNC13B	ENSMLUP00000014508	ENSMLUP00000005661	Protein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family.	Unc-13 homolog B.	0.859
LIN7C	UNC13C	ENSMLUP00000014508	ENSMLUP00000002426	Protein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family.	Unc-13 homolog C.	0.575
RIMS1	CASK	ENSMLUP00000021789	ENSMLUP00000002731	Regulating synaptic membrane exocytosis 1.	Calcium/calmodulin dependent serine protein kinase; Belongs to the MAGUK family.	0.878