STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GRB10Growth factor receptor bound protein 10. (552 aa)    
Predicted Functional Partners:
IGF1R
Tyrosine-protein kinase receptor.
    
 0.992
INSR
Tyrosine-protein kinase receptor.
    
 0.990
PIK3R1
Phosphoinositide-3-kinase regulatory subunit 1.
    
 0.983
NEDD4
NEDD4 E3 ubiquitin protein ligase.
    
 
 0.964
PIK3CA
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha; Belongs to the PI3/PI4-kinase family.
    
 0.959
G1P265_MYOLU
Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family.
     
 0.874
LOC102437790
Uncharacterized protein; Belongs to the PI3/PI4-kinase family.
     
 0.874
GRB2
Growth factor receptor bound protein 2.
    
 0.872
INS
Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
     
 0.866
GIGYF2
GRB10 interacting GYF protein 2.
    
 
 0.865
Your Current Organism:
Myotis lucifugus
NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat
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