STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AP1M2AP-1 complex subunit mu-2; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. (463 aa)    
Predicted Functional Partners:
AP1G2
AP-1 complex subunit gamma.
   
 0.999
AP1G1
AP-1 complex subunit gamma.
   
 0.997
AP1B1
AP complex subunit beta.
   
 0.997
AP1S1
AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.
    
 0.996
AP1S3
AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.
    
 0.991
AP1S2
AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.
    
 0.990
LOC102442976
Uncharacterized protein.
   
 0.977
AP4E1
AP-4 complex subunit epsilon; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system.
   
 0.950
AP4S1
AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.
    
 0.945
AP2B1
AP complex subunit beta.
    
 0.933
Your Current Organism:
Myotis lucifugus
NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.