SUPT16H protein (Myotis lucifugus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

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textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Myotis lucifugus

NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CTR9	G1Q195_MYOLU	ENSMLUP00000005685	ENSMLUP00000017478	CTR9 homolog, Paf1/RNA polymerase II complex component.	Transcription elongation factor SPT5.	0.945
CTR9	IWS1	ENSMLUP00000005685	ENSMLUP00000015475	CTR9 homolog, Paf1/RNA polymerase II complex component.	Interacts with SUPT6H, CTD assembly factor 1.	0.986
CTR9	LEO1	ENSMLUP00000005685	ENSMLUP00000003626	CTR9 homolog, Paf1/RNA polymerase II complex component.	LEO1 homolog, Paf1/RNA polymerase II complex component.	0.999
CTR9	PAF1	ENSMLUP00000005685	ENSMLUP00000002665	CTR9 homolog, Paf1/RNA polymerase II complex component.	PAF1 homolog, Paf1/RNA polymerase II complex component.	0.999
CTR9	POLR2A	ENSMLUP00000005685	ENSMLUP00000008299	CTR9 homolog, Paf1/RNA polymerase II complex component.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.972
CTR9	SSRP1	ENSMLUP00000005685	ENSMLUP00000006551	CTR9 homolog, Paf1/RNA polymerase II complex component.	FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...]	0.989
CTR9	SUPT16H	ENSMLUP00000005685	ENSMLUP00000007243	CTR9 homolog, Paf1/RNA polymerase II complex component.	SPT16 homolog, facilitates chromatin remodeling subunit.	0.994
CTR9	SUPT5H	ENSMLUP00000005685	ENSMLUP00000012650	CTR9 homolog, Paf1/RNA polymerase II complex component.	Transcription elongation factor SPT5.	0.945
CTR9	SUPT6H	ENSMLUP00000005685	ENSMLUP00000011327	CTR9 homolog, Paf1/RNA polymerase II complex component.	Transcription elongation factor spt6; Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII). Belongs to the SPT6 family.	0.983
CTR9	TNKS1BP1	ENSMLUP00000005685	ENSMLUP00000006525	CTR9 homolog, Paf1/RNA polymerase II complex component.	Tankyrase 1 binding protein 1.	0.970
G1Q195_MYOLU	CTR9	ENSMLUP00000017478	ENSMLUP00000005685	Transcription elongation factor SPT5.	CTR9 homolog, Paf1/RNA polymerase II complex component.	0.945
G1Q195_MYOLU	IWS1	ENSMLUP00000017478	ENSMLUP00000015475	Transcription elongation factor SPT5.	Interacts with SUPT6H, CTD assembly factor 1.	0.945
G1Q195_MYOLU	LEO1	ENSMLUP00000017478	ENSMLUP00000003626	Transcription elongation factor SPT5.	LEO1 homolog, Paf1/RNA polymerase II complex component.	0.966
G1Q195_MYOLU	PAF1	ENSMLUP00000017478	ENSMLUP00000002665	Transcription elongation factor SPT5.	PAF1 homolog, Paf1/RNA polymerase II complex component.	0.951
G1Q195_MYOLU	POLR2A	ENSMLUP00000017478	ENSMLUP00000008299	Transcription elongation factor SPT5.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.989
G1Q195_MYOLU	SSRP1	ENSMLUP00000017478	ENSMLUP00000006551	Transcription elongation factor SPT5.	FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...]	0.951
G1Q195_MYOLU	SUPT16H	ENSMLUP00000017478	ENSMLUP00000007243	Transcription elongation factor SPT5.	SPT16 homolog, facilitates chromatin remodeling subunit.	0.974
G1Q195_MYOLU	SUPT5H	ENSMLUP00000017478	ENSMLUP00000012650	Transcription elongation factor SPT5.	Transcription elongation factor SPT5.	0.542
G1Q195_MYOLU	SUPT6H	ENSMLUP00000017478	ENSMLUP00000011327	Transcription elongation factor SPT5.	Transcription elongation factor spt6; Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII). Belongs to the SPT6 family.	0.990
G1Q195_MYOLU	TNKS1BP1	ENSMLUP00000017478	ENSMLUP00000006525	Transcription elongation factor SPT5.	Tankyrase 1 binding protein 1.	0.937