L7N1F7_MYOLU protein (Myotis lucifugus) - STRING interaction network

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L7N1F7_MYOLU

Rad60-SLD domain-containing protein. (94 aa)

Predicted Functional Partners:

UBE2I

0.993

RANBP2

0.990

SAE1

0.967

PIAS4

0.960

SENP1

0.938

RANGAP1

0.937

SENP7

0.935

SENP6

0.935

UBA2

0.934

G1Q4D8_MYOLU

0.934

Your Current Organism:

Myotis lucifugus

NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
G1Q4D8_MYOLU	L7N1F7_MYOLU	ENSMLUP00000018571	ENSMLUP00000007426	SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family.	Rad60-SLD domain-containing protein.	0.934
G1Q4D8_MYOLU	PIAS4	ENSMLUP00000018571	ENSMLUP00000007884	SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family.	Protein inhibitor of activated STAT 4.	0.546
G1Q4D8_MYOLU	RANBP2	ENSMLUP00000018571	ENSMLUP00000005088	SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family.	RAN binding protein 2.	0.706
G1Q4D8_MYOLU	RANGAP1	ENSMLUP00000018571	ENSMLUP00000008128	SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family.	Ran GTPase activating protein 1.	0.539
G1Q4D8_MYOLU	SAE1	ENSMLUP00000018571	ENSMLUP00000009350	SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family.	SUMO1 activating enzyme subunit 1.	0.999
G1Q4D8_MYOLU	SENP1	ENSMLUP00000018571	ENSMLUP00000006015	SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family.	SUMO specific peptidase 1.	0.677
G1Q4D8_MYOLU	SENP6	ENSMLUP00000018571	ENSMLUP00000011906	SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family.	SUMO specific peptidase 6.	0.609
G1Q4D8_MYOLU	SENP7	ENSMLUP00000018571	ENSMLUP00000007839	SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family.	SUMO specific peptidase 7.	0.669
G1Q4D8_MYOLU	UBE2I	ENSMLUP00000018571	ENSMLUP00000007507	SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family.	Ubiquitin conjugating enzyme E2 I; Belongs to the ubiquitin-conjugating enzyme family.	0.985
L7N1F7_MYOLU	G1Q4D8_MYOLU	ENSMLUP00000007426	ENSMLUP00000018571	Rad60-SLD domain-containing protein.	SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family.	0.934
L7N1F7_MYOLU	PIAS4	ENSMLUP00000007426	ENSMLUP00000007884	Rad60-SLD domain-containing protein.	Protein inhibitor of activated STAT 4.	0.960
L7N1F7_MYOLU	RANBP2	ENSMLUP00000007426	ENSMLUP00000005088	Rad60-SLD domain-containing protein.	RAN binding protein 2.	0.990
L7N1F7_MYOLU	RANGAP1	ENSMLUP00000007426	ENSMLUP00000008128	Rad60-SLD domain-containing protein.	Ran GTPase activating protein 1.	0.937
L7N1F7_MYOLU	SAE1	ENSMLUP00000007426	ENSMLUP00000009350	Rad60-SLD domain-containing protein.	SUMO1 activating enzyme subunit 1.	0.967
L7N1F7_MYOLU	SENP1	ENSMLUP00000007426	ENSMLUP00000006015	Rad60-SLD domain-containing protein.	SUMO specific peptidase 1.	0.938
L7N1F7_MYOLU	SENP6	ENSMLUP00000007426	ENSMLUP00000011906	Rad60-SLD domain-containing protein.	SUMO specific peptidase 6.	0.935
L7N1F7_MYOLU	SENP7	ENSMLUP00000007426	ENSMLUP00000007839	Rad60-SLD domain-containing protein.	SUMO specific peptidase 7.	0.935
L7N1F7_MYOLU	UBA2	ENSMLUP00000007426	ENSMLUP00000002773	Rad60-SLD domain-containing protein.	SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family.	0.934
L7N1F7_MYOLU	UBE2I	ENSMLUP00000007426	ENSMLUP00000007507	Rad60-SLD domain-containing protein.	Ubiquitin conjugating enzyme E2 I; Belongs to the ubiquitin-conjugating enzyme family.	0.993
PIAS4	G1Q4D8_MYOLU	ENSMLUP00000007884	ENSMLUP00000018571	Protein inhibitor of activated STAT 4.	SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family.	0.546