MSC protein (Myotis lucifugus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Myotis lucifugus

NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat

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... as tabular text output:

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DMRT2	MSC	ENSMLUP00000010461	ENSMLUP00000007821	Doublesex and mab-3 related transcription factor 2.	Musculin.	0.557
LDB1	LDB2	ENSMLUP00000008417	ENSMLUP00000002450	LIM domain binding 1.	LIM domain binding 2.	0.852
LDB1	MSC	ENSMLUP00000008417	ENSMLUP00000007821	LIM domain binding 1.	Musculin.	0.663
LDB1	RUNX1	ENSMLUP00000008417	ENSMLUP00000005300	LIM domain binding 1.	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	0.686
LDB1	RUNX2	ENSMLUP00000008417	ENSMLUP00000000466	LIM domain binding 1.	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	0.653
LDB1	RUNX3	ENSMLUP00000008417	ENSMLUP00000003088	LIM domain binding 1.	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	0.653
LDB1	TCF12	ENSMLUP00000008417	ENSMLUP00000005682	LIM domain binding 1.	Transcription factor 12.	0.654
LDB1	TCF3	ENSMLUP00000008417	ENSMLUP00000010231	LIM domain binding 1.	Transcription factor 3.	0.852
LDB1	TCF4	ENSMLUP00000008417	ENSMLUP00000011764	LIM domain binding 1.	Transcription factor 4.	0.768
LDB2	LDB1	ENSMLUP00000002450	ENSMLUP00000008417	LIM domain binding 2.	LIM domain binding 1.	0.852
LDB2	MSC	ENSMLUP00000002450	ENSMLUP00000007821	LIM domain binding 2.	Musculin.	0.663
LDB2	RUNX1	ENSMLUP00000002450	ENSMLUP00000005300	LIM domain binding 2.	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	0.651
LDB2	RUNX2	ENSMLUP00000002450	ENSMLUP00000000466	LIM domain binding 2.	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	0.651
LDB2	RUNX3	ENSMLUP00000002450	ENSMLUP00000003088	LIM domain binding 2.	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	0.651
LDB2	TCF12	ENSMLUP00000002450	ENSMLUP00000005682	LIM domain binding 2.	Transcription factor 12.	0.652
LDB2	TCF3	ENSMLUP00000002450	ENSMLUP00000010231	LIM domain binding 2.	Transcription factor 3.	0.809
LDB2	TCF4	ENSMLUP00000002450	ENSMLUP00000011764	LIM domain binding 2.	Transcription factor 4.	0.652
MSC	DMRT2	ENSMLUP00000007821	ENSMLUP00000010461	Musculin.	Doublesex and mab-3 related transcription factor 2.	0.557
MSC	LDB1	ENSMLUP00000007821	ENSMLUP00000008417	Musculin.	LIM domain binding 1.	0.663
MSC	LDB2	ENSMLUP00000007821	ENSMLUP00000002450	Musculin.	LIM domain binding 2.	0.663