STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ESRRAEstrogen related receptor alpha. (424 aa)    
Predicted Functional Partners:
PPARGC1A
PPARG coactivator 1 alpha.
   
 0.996
NCOR1
Nuclear receptor corepressor 1.
    
 0.926
PPARGC1B
PPARG coactivator 1 beta.
    
 0.911
NRIP1
Nuclear receptor interacting protein 1.
    
 0.870
ESRRB
Estrogen related receptor beta.
  
 
 
0.825
TADA1
Transcriptional adaptor 1.
    
 0.799
ESRRG
Estrogen related receptor gamma.
  
 
 
0.798
MED1
Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
    
 0.778
NCOA3
Nuclear receptor coactivator.
    
 0.724
NCOA2
Nuclear receptor coactivator.
    
 0.717
Your Current Organism:
Myotis lucifugus
NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.