NKX2-2 protein (Myotis lucifugus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Myotis lucifugus

NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
G1PNJ4_MYOLU	NKX2-2	ENSMLUP00000012521	ENSMLUP00000008537	Uncharacterized protein.	NK2 homeobox 2.	0.783
G1PNJ4_MYOLU	PAX6	ENSMLUP00000012521	ENSMLUP00000005952	Uncharacterized protein.	Paired box 6.	0.527
G1PNJ4_MYOLU	TLE1	ENSMLUP00000012521	ENSMLUP00000002810	Uncharacterized protein.	TLE family member 1, transcriptional corepressor.	0.904
INS	NEUROG1	ENSMLUP00000003521	ENSMLUP00000004158	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Neurogenin 1.	0.613
INS	NEUROG3	ENSMLUP00000003521	ENSMLUP00000019233	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Neurogenin 3.	0.728
INS	NKX2-2	ENSMLUP00000003521	ENSMLUP00000008537	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	NK2 homeobox 2.	0.773
INS	PAX6	ENSMLUP00000003521	ENSMLUP00000005952	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Paired box 6.	0.878
NEUROG1	INS	ENSMLUP00000004158	ENSMLUP00000003521	Neurogenin 1.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.613
NEUROG1	NKX2-2	ENSMLUP00000004158	ENSMLUP00000008537	Neurogenin 1.	NK2 homeobox 2.	0.804
NEUROG1	OLIG3	ENSMLUP00000004158	ENSMLUP00000021956	Neurogenin 1.	Oligodendrocyte transcription factor 3.	0.514
NEUROG1	PAX6	ENSMLUP00000004158	ENSMLUP00000005952	Neurogenin 1.	Paired box 6.	0.803
NEUROG3	INS	ENSMLUP00000019233	ENSMLUP00000003521	Neurogenin 3.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.728
NEUROG3	NKX2-2	ENSMLUP00000019233	ENSMLUP00000008537	Neurogenin 3.	NK2 homeobox 2.	0.832
NEUROG3	OLIG3	ENSMLUP00000019233	ENSMLUP00000021956	Neurogenin 3.	Oligodendrocyte transcription factor 3.	0.514
NEUROG3	PAX6	ENSMLUP00000019233	ENSMLUP00000005952	Neurogenin 3.	Paired box 6.	0.868
NKX2-2	G1PNJ4_MYOLU	ENSMLUP00000008537	ENSMLUP00000012521	NK2 homeobox 2.	Uncharacterized protein.	0.783
NKX2-2	INS	ENSMLUP00000008537	ENSMLUP00000003521	NK2 homeobox 2.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.773
NKX2-2	NEUROG1	ENSMLUP00000008537	ENSMLUP00000004158	NK2 homeobox 2.	Neurogenin 1.	0.804
NKX2-2	NEUROG3	ENSMLUP00000008537	ENSMLUP00000019233	NK2 homeobox 2.	Neurogenin 3.	0.832
NKX2-2	OLIG3	ENSMLUP00000008537	ENSMLUP00000021956	NK2 homeobox 2.	Oligodendrocyte transcription factor 3.	0.815