STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IDEInsulin degrading enzyme; Belongs to the peptidase M16 family. (989 aa)    
Predicted Functional Partners:
INS
Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
    
 0.998
APP
Amyloid beta precursor protein.
    
 
 0.983
NPPB
Uncharacterized protein.
    
 
 0.914
TGFA
Transforming growth factor alpha.
    
 
 0.907
BACE1
Beta-secretase 1; Belongs to the peptidase A1 family.
     
 0.899
UBB
Uncharacterized protein.
    
  0.890
LOC102442670
Uncharacterized protein.
    
  0.890
ENSMLUP00000021652
annotation not available
    
  0.890
LOC102420450
Ubiquitin-like domain-containing protein.
    
  0.887
G1Q2S7_MYOLU
Ubiquitin-like domain-containing protein.
    
  0.887
Your Current Organism:
Myotis lucifugus
NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat
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