PDX1 protein (Myotis lucifugus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Myotis lucifugus

NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
FOXA2	INS	ENSMLUP00000017813	ENSMLUP00000003521	Forkhead box A2.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.686
FOXA2	PDX1	ENSMLUP00000017813	ENSMLUP00000009694	Forkhead box A2.	Pancreatic and duodenal homeobox 1.	0.885
GCK	HK2	ENSMLUP00000010946	ENSMLUP00000008223	Phosphotransferase.	Hexokinase 2.	0.861
GCK	INS	ENSMLUP00000010946	ENSMLUP00000003521	Phosphotransferase.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.684
GCK	PDX1	ENSMLUP00000010946	ENSMLUP00000009694	Phosphotransferase.	Pancreatic and duodenal homeobox 1.	0.936
HK2	GCK	ENSMLUP00000008223	ENSMLUP00000010946	Hexokinase 2.	Phosphotransferase.	0.861
HK2	INS	ENSMLUP00000008223	ENSMLUP00000003521	Hexokinase 2.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.558
HK2	PDX1	ENSMLUP00000008223	ENSMLUP00000009694	Hexokinase 2.	Pancreatic and duodenal homeobox 1.	0.831
HK2	PRKACA	ENSMLUP00000008223	ENSMLUP00000007530	Hexokinase 2.	Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily.	0.503
HK2	PRKACB	ENSMLUP00000008223	ENSMLUP00000003022	Hexokinase 2.	Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily.	0.503
INS	FOXA2	ENSMLUP00000003521	ENSMLUP00000017813	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Forkhead box A2.	0.686
INS	GCK	ENSMLUP00000003521	ENSMLUP00000010946	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Phosphotransferase.	0.684
INS	HK2	ENSMLUP00000003521	ENSMLUP00000008223	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Hexokinase 2.	0.558
INS	MAFB	ENSMLUP00000003521	ENSMLUP00000002748	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	MAF bZIP transcription factor B.	0.837
INS	PDX1	ENSMLUP00000003521	ENSMLUP00000009694	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Pancreatic and duodenal homeobox 1.	0.962
INS	PRKACA	ENSMLUP00000003521	ENSMLUP00000007530	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily.	0.585
INS	PRKACB	ENSMLUP00000003521	ENSMLUP00000003022	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily.	0.585
MAFB	INS	ENSMLUP00000002748	ENSMLUP00000003521	MAF bZIP transcription factor B.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.837
MAFB	PDX1	ENSMLUP00000002748	ENSMLUP00000009694	MAF bZIP transcription factor B.	Pancreatic and duodenal homeobox 1.	0.950
NAV3	PDX1	ENSMLUP00000009508	ENSMLUP00000009694	Neuron navigator 3.	Pancreatic and duodenal homeobox 1.	0.866