STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (396 aa)    
Predicted Functional Partners:
CDON
Cell adhesion associated, oncogene regulated.
    
 0.995
PTCH1
Patched 1.
   
 0.993
PTCH2
Patched 2.
   
 0.988
HHIP
Hedgehog interacting protein.
    
 0.986
BOC
BOC cell adhesion associated, oncogene regulated.
    
 0.979
DISP1
Dispatched RND transporter family member 1.
   
 0.971
DISP2
Dispatched RND transporter family member 2.
   
 0.932
LRP2
LDL receptor related protein 2.
     
 0.917
DISP3
Dispatched RND transporter family member 3.
    
 0.913
GPC3
Glypican 3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.
    
 0.912
Your Current Organism:
Myotis lucifugus
NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.