PLCB4 protein (Myotis lucifugus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Myotis lucifugus

NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat

Export your current network:

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file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

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same PNG format, but at higher resolution

... as a vector graphic:

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SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

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TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GNA11	GNA14	ENSMLUP00000006396	ENSMLUP00000003405	G protein subunit alpha 11.	G protein subunit alpha 14.	0.900
GNA11	GNAI2	ENSMLUP00000006396	ENSMLUP00000002148	G protein subunit alpha 11.	G protein subunit alpha i2.	0.823
GNA11	GNAI3	ENSMLUP00000006396	ENSMLUP00000003976	G protein subunit alpha 11.	G protein subunit alpha i3.	0.824
GNA11	GNAQ	ENSMLUP00000006396	ENSMLUP00000003410	G protein subunit alpha 11.	G protein subunit alpha q.	0.900
GNA11	GNAT3	ENSMLUP00000006396	ENSMLUP00000018925	G protein subunit alpha 11.	G protein subunit alpha transducin 3.	0.690
GNA11	GNB3	ENSMLUP00000006396	ENSMLUP00000006150	G protein subunit alpha 11.	G protein subunit beta 3.	0.941
GNA11	GNG13	ENSMLUP00000006396	ENSMLUP00000019806	G protein subunit alpha 11.	G protein subunit gamma 13.	0.886
GNA11	ITPR2	ENSMLUP00000006396	ENSMLUP00000010450	G protein subunit alpha 11.	Inositol 1,4,5-trisphosphate receptor type 2.	0.447
GNA11	ITPR3	ENSMLUP00000006396	ENSMLUP00000010891	G protein subunit alpha 11.	Inositol 1,4,5-trisphosphate receptor type 3.	0.447
GNA11	PLCB4	ENSMLUP00000006396	ENSMLUP00000011388	G protein subunit alpha 11.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.	0.986
GNA14	GNA11	ENSMLUP00000003405	ENSMLUP00000006396	G protein subunit alpha 14.	G protein subunit alpha 11.	0.900
GNA14	GNAI2	ENSMLUP00000003405	ENSMLUP00000002148	G protein subunit alpha 14.	G protein subunit alpha i2.	0.738
GNA14	GNAI3	ENSMLUP00000003405	ENSMLUP00000003976	G protein subunit alpha 14.	G protein subunit alpha i3.	0.738
GNA14	GNAQ	ENSMLUP00000003405	ENSMLUP00000003410	G protein subunit alpha 14.	G protein subunit alpha q.	0.900
GNA14	GNAT3	ENSMLUP00000003405	ENSMLUP00000018925	G protein subunit alpha 14.	G protein subunit alpha transducin 3.	0.687
GNA14	GNB3	ENSMLUP00000003405	ENSMLUP00000006150	G protein subunit alpha 14.	G protein subunit beta 3.	0.939
GNA14	GNG13	ENSMLUP00000003405	ENSMLUP00000019806	G protein subunit alpha 14.	G protein subunit gamma 13.	0.886
GNA14	PLCB4	ENSMLUP00000003405	ENSMLUP00000011388	G protein subunit alpha 14.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.	0.986
GNAI2	GNA11	ENSMLUP00000002148	ENSMLUP00000006396	G protein subunit alpha i2.	G protein subunit alpha 11.	0.823
GNAI2	GNA14	ENSMLUP00000002148	ENSMLUP00000003405	G protein subunit alpha i2.	G protein subunit alpha 14.	0.738