LYL1 protein (Myotis lucifugus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Myotis lucifugus

NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EP300	GATA2	ENSMLUP00000013493	ENSMLUP00000005028	E1A binding protein p300.	GATA binding protein 2.	0.847
EP300	LYL1	ENSMLUP00000013493	ENSMLUP00000011652	E1A binding protein p300.	LYL1 basic helix-loop-helix family member.	0.710
EP300	RUNX1	ENSMLUP00000013493	ENSMLUP00000005300	E1A binding protein p300.	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	0.936
EP300	TAL1	ENSMLUP00000013493	ENSMLUP00000005835	E1A binding protein p300.	TAL bHLH transcription factor 1, erythroid differentiation factor.	0.930
EP300	TCF12	ENSMLUP00000013493	ENSMLUP00000005682	E1A binding protein p300.	Transcription factor 12.	0.896
EP300	TCF3	ENSMLUP00000013493	ENSMLUP00000010231	E1A binding protein p300.	Transcription factor 3.	0.970
EP300	TCF4	ENSMLUP00000013493	ENSMLUP00000011764	E1A binding protein p300.	Transcription factor 4.	0.896
GATA2	EP300	ENSMLUP00000005028	ENSMLUP00000013493	GATA binding protein 2.	E1A binding protein p300.	0.847
GATA2	LDB1	ENSMLUP00000005028	ENSMLUP00000008417	GATA binding protein 2.	LIM domain binding 1.	0.863
GATA2	LDB2	ENSMLUP00000005028	ENSMLUP00000002450	GATA binding protein 2.	LIM domain binding 2.	0.863
GATA2	LMO2	ENSMLUP00000005028	ENSMLUP00000003354	GATA binding protein 2.	LIM domain only 2.	0.902
GATA2	LYL1	ENSMLUP00000005028	ENSMLUP00000011652	GATA binding protein 2.	LYL1 basic helix-loop-helix family member.	0.700
GATA2	RUNX1	ENSMLUP00000005028	ENSMLUP00000005300	GATA binding protein 2.	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	0.899
GATA2	TAL1	ENSMLUP00000005028	ENSMLUP00000005835	GATA binding protein 2.	TAL bHLH transcription factor 1, erythroid differentiation factor.	0.991
GATA2	TCF12	ENSMLUP00000005028	ENSMLUP00000005682	GATA binding protein 2.	Transcription factor 12.	0.830
GATA2	TCF3	ENSMLUP00000005028	ENSMLUP00000010231	GATA binding protein 2.	Transcription factor 3.	0.761
GATA2	TCF4	ENSMLUP00000005028	ENSMLUP00000011764	GATA binding protein 2.	Transcription factor 4.	0.830
LDB1	GATA2	ENSMLUP00000008417	ENSMLUP00000005028	LIM domain binding 1.	GATA binding protein 2.	0.863
LDB1	LDB2	ENSMLUP00000008417	ENSMLUP00000002450	LIM domain binding 1.	LIM domain binding 2.	0.852
LDB1	LMO2	ENSMLUP00000008417	ENSMLUP00000003354	LIM domain binding 1.	LIM domain only 2.	0.995