STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HRGHistidine rich glycoprotein. (523 aa)    
Predicted Functional Partners:
PLG
Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...]
   
 0.998
F12
Coagulation factor XII.
   
 0.991
PLAU
Plasminogen activator, urokinase.
    
 0.964
F13B
Coagulation factor XIII B chain.
   
 0.918
AGXT
Serine--pyruvate aminotransferase.
   
    0.907
APOH
Apolipoprotein H.
   
 0.906
LOC102441621
Solute carrier organic anion transporter family member.
   
    0.898
FGA
Fibrinogen alpha chain.
   
 0.867
KNG1
Kininogen 1.
 
 
 
 0.863
KLKB1
Kallikrein B1; Belongs to the peptidase S1 family.
   
 0.861
Your Current Organism:
Myotis lucifugus
NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat
Server load: low (18%) [HD]