ITGA4 protein (Myotis lucifugus) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

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[Homology]

Score

ITGA4

Integrin subunit alpha 4; Belongs to the integrin alpha chain family. (1036 aa)

Predicted Functional Partners:

ITGB7

0.999

ITGB1

0.999

PXN

0.985

ITGB2

0.980

ITGB3

0.980

VCAM1

0.972

ITGB5

0.969

ITGB8

0.968

FN1

0.966

MADCAM1

0.966

Your Current Organism:

Myotis lucifugus

NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
FN1	ITGA4	ENSMLUP00000001687	ENSMLUP00000012938	Fibronectin 1.	Integrin subunit alpha 4; Belongs to the integrin alpha chain family.	0.966
FN1	ITGB1	ENSMLUP00000001687	ENSMLUP00000016023	Fibronectin 1.	Integrin beta; Belongs to the integrin beta chain family.	0.997
FN1	ITGB2	ENSMLUP00000001687	ENSMLUP00000002875	Fibronectin 1.	Integrin beta.	0.980
FN1	ITGB3	ENSMLUP00000001687	ENSMLUP00000018227	Fibronectin 1.	Integrin beta; Belongs to the integrin beta chain family.	0.996
FN1	ITGB5	ENSMLUP00000001687	ENSMLUP00000002158	Fibronectin 1.	Integrin beta; Belongs to the integrin beta chain family.	0.987
FN1	ITGB7	ENSMLUP00000001687	ENSMLUP00000015756	Fibronectin 1.	Integrin beta; Belongs to the integrin beta chain family.	0.977
FN1	ITGB8	ENSMLUP00000001687	ENSMLUP00000008114	Fibronectin 1.	Integrin beta; Belongs to the integrin beta chain family.	0.903
FN1	VCAM1	ENSMLUP00000001687	ENSMLUP00000011488	Fibronectin 1.	Vascular cell adhesion molecule 1.	0.504
ITGA4	FN1	ENSMLUP00000012938	ENSMLUP00000001687	Integrin subunit alpha 4; Belongs to the integrin alpha chain family.	Fibronectin 1.	0.966
ITGA4	ITGB1	ENSMLUP00000012938	ENSMLUP00000016023	Integrin subunit alpha 4; Belongs to the integrin alpha chain family.	Integrin beta; Belongs to the integrin beta chain family.	0.999
ITGA4	ITGB2	ENSMLUP00000012938	ENSMLUP00000002875	Integrin subunit alpha 4; Belongs to the integrin alpha chain family.	Integrin beta.	0.980
ITGA4	ITGB3	ENSMLUP00000012938	ENSMLUP00000018227	Integrin subunit alpha 4; Belongs to the integrin alpha chain family.	Integrin beta; Belongs to the integrin beta chain family.	0.980
ITGA4	ITGB5	ENSMLUP00000012938	ENSMLUP00000002158	Integrin subunit alpha 4; Belongs to the integrin alpha chain family.	Integrin beta; Belongs to the integrin beta chain family.	0.969
ITGA4	ITGB7	ENSMLUP00000012938	ENSMLUP00000015756	Integrin subunit alpha 4; Belongs to the integrin alpha chain family.	Integrin beta; Belongs to the integrin beta chain family.	0.999
ITGA4	ITGB8	ENSMLUP00000012938	ENSMLUP00000008114	Integrin subunit alpha 4; Belongs to the integrin alpha chain family.	Integrin beta; Belongs to the integrin beta chain family.	0.968
ITGA4	MADCAM1	ENSMLUP00000012938	ENSMLUP00000011585	Integrin subunit alpha 4; Belongs to the integrin alpha chain family.	Ig-like domain-containing protein.	0.966
ITGA4	PXN	ENSMLUP00000012938	ENSMLUP00000014109	Integrin subunit alpha 4; Belongs to the integrin alpha chain family.	Paxillin; Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Belongs to the paxillin family.	0.985
ITGA4	VCAM1	ENSMLUP00000012938	ENSMLUP00000011488	Integrin subunit alpha 4; Belongs to the integrin alpha chain family.	Vascular cell adhesion molecule 1.	0.972
ITGB1	FN1	ENSMLUP00000016023	ENSMLUP00000001687	Integrin beta; Belongs to the integrin beta chain family.	Fibronectin 1.	0.997
ITGB1	ITGA4	ENSMLUP00000016023	ENSMLUP00000012938	Integrin beta; Belongs to the integrin beta chain family.	Integrin subunit alpha 4; Belongs to the integrin alpha chain family.	0.999