STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RIPK3Receptor interacting serine/threonine kinase 3; Belongs to the protein kinase superfamily. (499 aa)    
Predicted Functional Partners:
RIPK1
Receptor interacting serine/threonine kinase 1.
  
 
0.999
CASP8
Caspase 8; Belongs to the peptidase C14A family.
   
 0.998
TNF
Tumor necrosis factor; Belongs to the tumor necrosis factor family.
    
 0.994
TRADD
TNFRSF1A associated via death domain.
    
 0.982
G1PVX2_MYOLU
Uncharacterized protein.
    
 0.974
PELI1
E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins.
    
 0.973
STUB1
STIP1 homology and U-box containing protein 1.
    
 0.966
PRKN
Parkin RBR E3 ubiquitin protein ligase.
    
 0.965
MLKL
Mixed lineage kinase domain like pseudokinase.
  
 
0.958
OGT
O-linked N-acetylglucosamine (GlcNAc) transferase.
    
  0.954
Your Current Organism:
Myotis lucifugus
NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.