node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
HMGCL | HMGCLL1 | ENSMLUP00000004813 | ENSMLUP00000002461 | 3-hydroxy-3-methylglutaryl-CoA lyase. | 3-hydroxymethyl-3-methylglutaryl-CoA lyase like 1. | 0.875 |
HMGCL | HMGCR | ENSMLUP00000004813 | ENSMLUP00000003861 | 3-hydroxy-3-methylglutaryl-CoA lyase. | 3-hydroxy-3-methylglutaryl coenzyme A reductase. | 0.857 |
HMGCL | HMGCS1 | ENSMLUP00000004813 | ENSMLUP00000002990 | 3-hydroxy-3-methylglutaryl-CoA lyase. | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | 0.937 |
HMGCL | HMGCS2 | ENSMLUP00000004813 | ENSMLUP00000002732 | 3-hydroxy-3-methylglutaryl-CoA lyase. | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | 0.968 |
HMGCL | MVK | ENSMLUP00000004813 | ENSMLUP00000014836 | 3-hydroxy-3-methylglutaryl-CoA lyase. | Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily. | 0.886 |
HMGCLL1 | HMGCL | ENSMLUP00000002461 | ENSMLUP00000004813 | 3-hydroxymethyl-3-methylglutaryl-CoA lyase like 1. | 3-hydroxy-3-methylglutaryl-CoA lyase. | 0.875 |
HMGCLL1 | HMGCR | ENSMLUP00000002461 | ENSMLUP00000003861 | 3-hydroxymethyl-3-methylglutaryl-CoA lyase like 1. | 3-hydroxy-3-methylglutaryl coenzyme A reductase. | 0.857 |
HMGCLL1 | HMGCS1 | ENSMLUP00000002461 | ENSMLUP00000002990 | 3-hydroxymethyl-3-methylglutaryl-CoA lyase like 1. | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | 0.918 |
HMGCLL1 | HMGCS2 | ENSMLUP00000002461 | ENSMLUP00000002732 | 3-hydroxymethyl-3-methylglutaryl-CoA lyase like 1. | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | 0.933 |
HMGCLL1 | MVK | ENSMLUP00000002461 | ENSMLUP00000014836 | 3-hydroxymethyl-3-methylglutaryl-CoA lyase like 1. | Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily. | 0.886 |
HMGCR | HMGCL | ENSMLUP00000003861 | ENSMLUP00000004813 | 3-hydroxy-3-methylglutaryl coenzyme A reductase. | 3-hydroxy-3-methylglutaryl-CoA lyase. | 0.857 |
HMGCR | HMGCLL1 | ENSMLUP00000003861 | ENSMLUP00000002461 | 3-hydroxy-3-methylglutaryl coenzyme A reductase. | 3-hydroxymethyl-3-methylglutaryl-CoA lyase like 1. | 0.857 |
HMGCR | HMGCS1 | ENSMLUP00000003861 | ENSMLUP00000002990 | 3-hydroxy-3-methylglutaryl coenzyme A reductase. | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | 0.998 |
HMGCR | HMGCS2 | ENSMLUP00000003861 | ENSMLUP00000002732 | 3-hydroxy-3-methylglutaryl coenzyme A reductase. | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | 0.996 |
HMGCR | LOC102431363 | ENSMLUP00000003861 | ENSMLUP00000022548 | 3-hydroxy-3-methylglutaryl coenzyme A reductase. | Nudix hydrolase domain-containing protein. | 0.905 |
HMGCR | MVD | ENSMLUP00000003861 | ENSMLUP00000008095 | 3-hydroxy-3-methylglutaryl coenzyme A reductase. | Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes. | 0.941 |
HMGCR | MVK | ENSMLUP00000003861 | ENSMLUP00000014836 | 3-hydroxy-3-methylglutaryl coenzyme A reductase. | Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily. | 0.975 |
HMGCR | PMVK | ENSMLUP00000003861 | ENSMLUP00000002161 | 3-hydroxy-3-methylglutaryl coenzyme A reductase. | Phosphomevalonate kinase. | 0.680 |
HMGCS1 | HMGCL | ENSMLUP00000002990 | ENSMLUP00000004813 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | 3-hydroxy-3-methylglutaryl-CoA lyase. | 0.937 |
HMGCS1 | HMGCLL1 | ENSMLUP00000002990 | ENSMLUP00000002461 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | 3-hydroxymethyl-3-methylglutaryl-CoA lyase like 1. | 0.918 |