STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CBLCCbl proto-oncogene C. (306 aa)    
Predicted Functional Partners:
G1P5B5_MYOLU
Uncharacterized protein.
   
 0.994
MST1R
Macrophage stimulating 1 receptor.
   
 0.991
MET
MET proto-oncogene, receptor tyrosine kinase.
   
 0.990
SH3KBP1
SH3 domain containing kinase binding protein 1.
    
 0.960
IGF1R
Tyrosine-protein kinase receptor.
    
 0.925
CRK
CRK proto-oncogene, adaptor protein.
    
 0.912
FGFR4
Fibroblast growth factor receptor.
    
 0.912
PDGFRA
Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development.
    
 0.912
CRKL
CRK like proto-oncogene, adaptor protein.
    
 0.912
SPRY4
Sprouty RTK signaling antagonist 4.
    
 0.912
Your Current Organism:
Myotis lucifugus
NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.