Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSMLUP00000018160annotation not available (136 aa)    
Predicted Functional Partners:
H2AX
Histone H2A; Belongs to the histone H2A family.
   
 0.911
KDM6A
Lysine demethylase 6A.
   
 0.898
KDM6B
Lysine demethylase 6B.
   
 0.898
LOC106698231
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
 
 
 0.896
ENSMLUP00000017704
annotation not available
 
 
 0.896
ENSMLUP00000020187
annotation not available
 
 
 0.896
LOC102424579
annotation not available
 
 
 0.896
ENSMLUP00000022553
annotation not available
 
 
 0.896
SETD2
SET domain containing 2, histone lysine methyltransferase.
    
 0.860
ARID4A
AT-rich interaction domain 4A.
   
 0.859
Your Current Organism:
Myotis lucifugus
NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat
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