STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HBE1Globin B1; Belongs to the globin family. (147 aa)    
Predicted Functional Partners:
HBZ
Hemoglobin subunit zeta; Belongs to the globin family.
  
0.984
LOC102424357
GLOBIN domain-containing protein; Belongs to the globin family.
  
0.983
LOC102424877
GLOBIN domain-containing protein; Belongs to the globin family.
  
0.983
HBQ1
Hemoglobin subunit theta 1; Belongs to the globin family.
  
0.975
LOC102430960
Globin A1; Belongs to the globin family.
  
0.769
ENSMLUP00000022143
annotation not available
  
0.769
CYB5R4
Cytochrome b5 reductase 4.
   
 0.743
AHSP
Alpha hemoglobin stabilizing protein.
   
 
 0.718
APOB
Apolipoprotein B.
   
 
 0.646
LOC102438213
Haptoglobin; As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidly cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pathway.
    
 0.575
Your Current Organism:
Myotis lucifugus
NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.