G1Q4R9_MYOLU protein (Myotis lucifugus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

G1Q4R9_MYOLU

Small ubiquitin-related modifier. (95 aa)

Predicted Functional Partners:

UBE2I

0.993

RANBP2

0.990

SAE1

0.967

PIAS4

0.960

SENP1

0.938

RANGAP1

0.937

SENP7

0.935

SENP6

0.935

UBA2

0.934

G1Q4D8_MYOLU

0.934

Your Current Organism:

Myotis lucifugus

NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
G1Q4D8_MYOLU	G1Q4R9_MYOLU	ENSMLUP00000018571	ENSMLUP00000018702	SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family.	Small ubiquitin-related modifier.	0.934
G1Q4D8_MYOLU	PIAS4	ENSMLUP00000018571	ENSMLUP00000007884	SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family.	Protein inhibitor of activated STAT 4.	0.546
G1Q4D8_MYOLU	RANBP2	ENSMLUP00000018571	ENSMLUP00000005088	SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family.	RAN binding protein 2.	0.706
G1Q4D8_MYOLU	RANGAP1	ENSMLUP00000018571	ENSMLUP00000008128	SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family.	Ran GTPase activating protein 1.	0.539
G1Q4D8_MYOLU	SAE1	ENSMLUP00000018571	ENSMLUP00000009350	SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family.	SUMO1 activating enzyme subunit 1.	0.999
G1Q4D8_MYOLU	SENP1	ENSMLUP00000018571	ENSMLUP00000006015	SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family.	SUMO specific peptidase 1.	0.677
G1Q4D8_MYOLU	SENP6	ENSMLUP00000018571	ENSMLUP00000011906	SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family.	SUMO specific peptidase 6.	0.609
G1Q4D8_MYOLU	SENP7	ENSMLUP00000018571	ENSMLUP00000007839	SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family.	SUMO specific peptidase 7.	0.669
G1Q4D8_MYOLU	UBE2I	ENSMLUP00000018571	ENSMLUP00000007507	SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family.	Ubiquitin conjugating enzyme E2 I; Belongs to the ubiquitin-conjugating enzyme family.	0.985
G1Q4R9_MYOLU	G1Q4D8_MYOLU	ENSMLUP00000018702	ENSMLUP00000018571	Small ubiquitin-related modifier.	SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family.	0.934
G1Q4R9_MYOLU	PIAS4	ENSMLUP00000018702	ENSMLUP00000007884	Small ubiquitin-related modifier.	Protein inhibitor of activated STAT 4.	0.960
G1Q4R9_MYOLU	RANBP2	ENSMLUP00000018702	ENSMLUP00000005088	Small ubiquitin-related modifier.	RAN binding protein 2.	0.990
G1Q4R9_MYOLU	RANGAP1	ENSMLUP00000018702	ENSMLUP00000008128	Small ubiquitin-related modifier.	Ran GTPase activating protein 1.	0.937
G1Q4R9_MYOLU	SAE1	ENSMLUP00000018702	ENSMLUP00000009350	Small ubiquitin-related modifier.	SUMO1 activating enzyme subunit 1.	0.967
G1Q4R9_MYOLU	SENP1	ENSMLUP00000018702	ENSMLUP00000006015	Small ubiquitin-related modifier.	SUMO specific peptidase 1.	0.938
G1Q4R9_MYOLU	SENP6	ENSMLUP00000018702	ENSMLUP00000011906	Small ubiquitin-related modifier.	SUMO specific peptidase 6.	0.935
G1Q4R9_MYOLU	SENP7	ENSMLUP00000018702	ENSMLUP00000007839	Small ubiquitin-related modifier.	SUMO specific peptidase 7.	0.935
G1Q4R9_MYOLU	UBA2	ENSMLUP00000018702	ENSMLUP00000002773	Small ubiquitin-related modifier.	SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family.	0.934
G1Q4R9_MYOLU	UBE2I	ENSMLUP00000018702	ENSMLUP00000007507	Small ubiquitin-related modifier.	Ubiquitin conjugating enzyme E2 I; Belongs to the ubiquitin-conjugating enzyme family.	0.993
PIAS4	G1Q4D8_MYOLU	ENSMLUP00000007884	ENSMLUP00000018571	Protein inhibitor of activated STAT 4.	SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family.	0.546