STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
G1Q6T7_MYOLUUncharacterized protein; Belongs to the peptidase C14A family. (285 aa)    
Predicted Functional Partners:
PYCARD
PYD and CARD domain containing.
   
 0.971
IL1B
Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.
   
 0.953
NLRC4
NLR family CARD domain containing 4.
    
 0.953
G1Q6X4_MYOLU
Uncharacterized protein.
   
 0.930
CASP8
Caspase 8; Belongs to the peptidase C14A family.
   
0.917
APAF1
Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.
    
 0.914
MEFV
MEFV innate immuity regulator, pyrin.
    
 0.911
G1PCW0_MYOLU
Uncharacterized protein.
    
 0.897
IL1A
Interleukin-1; Belongs to the IL-1 family.
   
 0.891
NLRP10
NLR family pyrin domain containing 10.
   
 0.880
Your Current Organism:
Myotis lucifugus
NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat
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