STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
G1QAZ2_MYOLUUncharacterized protein. (879 aa)    
Predicted Functional Partners:
HBZ
Hemoglobin subunit zeta; Belongs to the globin family.
    
 0.842
VTCN1
V-set domain containing T cell activation inhibitor 1.
    
 
 0.705
DR1
Down-regulator of transcription 1.
      
 0.703
NDUFV3
NADH:ubiquinone oxidoreductase subunit V3.
      
 0.689
BCL2L15
BCL2 like 15.
      
 0.681
LOC102438213
Haptoglobin; As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidly cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pathway.
   
 0.632
LOC102420500
Uncharacterized protein.
   
 0.630
ITPRID1
ITPR interacting domain containing 1.
      
 0.603
FOLH1
Folate hydrolase 1.
    
 0.598
CD47
CD47 molecule.
   
 0.596
Your Current Organism:
Myotis lucifugus
NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.