NEUROD1 protein (Myotis lucifugus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

NEUROD1

Neurogenic differentiation factor. (357 aa)

Predicted Functional Partners:

PAX6

0.775

PAX4

0.741

FOXG1

0.708

GCK

0.698

RFX6

0.681

INSM2

0.681

TCF3

0.677

NKX2-2

0.659

HES1

0.652

INS

0.644

Your Current Organism:

Myotis lucifugus

NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
FOXG1	NEUROD1	ENSMLUP00000017421	ENSMLUP00000020920	Uncharacterized protein.	Neurogenic differentiation factor.	0.708
FOXG1	PAX4	ENSMLUP00000017421	ENSMLUP00000019100	Uncharacterized protein.	Paired box 4.	0.492
FOXG1	PAX6	ENSMLUP00000017421	ENSMLUP00000005952	Uncharacterized protein.	Paired box 6.	0.859
GCK	INS	ENSMLUP00000010946	ENSMLUP00000003521	Phosphotransferase.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.721
GCK	NEUROD1	ENSMLUP00000010946	ENSMLUP00000020920	Phosphotransferase.	Neurogenic differentiation factor.	0.698
GCK	PAX4	ENSMLUP00000010946	ENSMLUP00000019100	Phosphotransferase.	Paired box 4.	0.675
GCK	RFX6	ENSMLUP00000010946	ENSMLUP00000006098	Phosphotransferase.	Regulatory factor X6.	0.611
HES1	NEUROD1	ENSMLUP00000007790	ENSMLUP00000020920	Hes family bHLH transcription factor 1.	Neurogenic differentiation factor.	0.652
HES1	TCF3	ENSMLUP00000007790	ENSMLUP00000010231	Hes family bHLH transcription factor 1.	Transcription factor 3.	0.435
INS	GCK	ENSMLUP00000003521	ENSMLUP00000010946	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Phosphotransferase.	0.721
INS	NEUROD1	ENSMLUP00000003521	ENSMLUP00000020920	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Neurogenic differentiation factor.	0.644
INS	NKX2-2	ENSMLUP00000003521	ENSMLUP00000008537	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	NK2 homeobox 2.	0.805
INS	PAX4	ENSMLUP00000003521	ENSMLUP00000019100	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Paired box 4.	0.884
INS	PAX6	ENSMLUP00000003521	ENSMLUP00000005952	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Paired box 6.	0.842
INS	RFX6	ENSMLUP00000003521	ENSMLUP00000006098	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Regulatory factor X6.	0.747
INSM2	NEUROD1	ENSMLUP00000017897	ENSMLUP00000020920	INSM transcriptional repressor 2.	Neurogenic differentiation factor.	0.681
INSM2	PAX4	ENSMLUP00000017897	ENSMLUP00000019100	INSM transcriptional repressor 2.	Paired box 4.	0.539
INSM2	PAX6	ENSMLUP00000017897	ENSMLUP00000005952	INSM transcriptional repressor 2.	Paired box 6.	0.476
INSM2	RFX6	ENSMLUP00000017897	ENSMLUP00000006098	INSM transcriptional repressor 2.	Regulatory factor X6.	0.448
NEUROD1	FOXG1	ENSMLUP00000020920	ENSMLUP00000017421	Neurogenic differentiation factor.	Uncharacterized protein.	0.708