STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RNF212BRing finger protein 212B. (301 aa)    
Predicted Functional Partners:
OR10G3
Olfactory receptor family 10 subfamily G member 3.
      
 0.715
TOX4
TOX high mobility group box family member 4.
      
 0.622
SUPT16H
SPT16 homolog, facilitates chromatin remodeling subunit.
      
 0.612
SPO11
SPO11 initiator of meiotic double stranded breaks.
   
 
 0.579
RPGRIP1
RPGR interacting protein 1.
      
 0.573
TEX11
Testis expressed 11.
    
 
 0.567
CHD8
Chromodomain-helicase-DNA-binding protein 8; DNA helicase that acts as a chromatin remodeling factor and regulates transcription. Acts as a transcription repressor by remodeling chromatin structure and recruiting histone H1 to target genes. Suppresses p53/TP53-mediated apoptosis by recruiting histone H1 and preventing p53/TP53 transactivation activity. Acts as a negative regulator of Wnt signaling pathway by regulating beta-catenin (CTNNB1) activity. Negatively regulates CTNNB1-targeted gene expression by being recruited specifically to the promoter regions of several CTNNB1 responsive [...]
    
 
 0.534
SALL2
Spalt like transcription factor 2.
      
 0.531
REC114
Uncharacterized protein.
    
 
 0.520
REC8
REC8 meiotic recombination protein.
    
 
 0.515
Your Current Organism:
Myotis lucifugus
NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.