STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
WEE1WEE1 G2 checkpoint kinase. (648 aa)    
Predicted Functional Partners:
CDK2
Cyclin dependent kinase 2; Belongs to the protein kinase superfamily.
   
0.994
CDK1
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
   
 0.994
G1QCG2_MYOLU
Protein kinase domain-containing protein.
   
 0.994
CCNA1
Cyclin A1; Belongs to the cyclin family.
   
 0.991
PLK1
Serine/threonine-protein kinase PLK.
   
0.987
CHEK1
Checkpoint kinase 1; Belongs to the protein kinase superfamily.
   
0.972
CCNB1
Cyclin B1; Belongs to the cyclin family.
   
 0.958
CCNB2
Cyclin B2; Belongs to the cyclin family.
   
 0.958
CNTD2
Cyclin N-terminal domain containing 2; Belongs to the cyclin family.
   
 0.958
PRMT5
Protein arginine N-methyltransferase 5; Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA); Belongs to the class I-like SAM-binding methyltransferase superfamily.
    
 0.931
Your Current Organism:
Myotis lucifugus
NCBI taxonomy Id: 59463
Other names: M. lucifugus, little brown bat
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.