STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AIE83343.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (271 aa)    
Predicted Functional Partners:
AIE83265.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.600
AIE82996.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.591
AIE82051.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.539
AIE82674.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.539
AIE83089.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.531
AIE82962.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.523
AIE83344.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.495
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
       0.433
AIE82734.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.431
AIE83351.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.425
Your Current Organism:
Actinotignum schaalii
NCBI taxonomy Id: 59505
Other names: A. schaalii, Actinobaculum schaalii, CCM 4738, CCUG 27420, CIP 105739, DSM 15541, LMG 18293, LMG:18293
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.