STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KLU06990.1Soluble pyridine nucleotide transhydrogenase. (440 aa)    
Predicted Functional Partners:
KLU07030.1
Glutamate synthase [NADPH] large chain.
    
 0.956
nadK
NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
     
 0.955
nadE
NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
    
 0.919
cobB
NAD-dependent protein deacetylase of SIR2 family; Belongs to the sirtuin family. Class III subfamily.
    
 0.912
KLU05322.1
Dihydrolipoamide succinyltransferase component (E2) of 2-oxoglutarate dehydrogenase complex; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).
 0.878
KLU01882.1
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
 0.878
KLU01493.1
2-oxoglutarate dehydrogenase E1 component.
 
 0.865
KLU06904.1
Membrane protein containing SNARE domain protein.
      0.845
KLU06698.1
NAD(P) transhydrogenase subunit beta; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.
     
 0.830
KLU06696.1
NAD(P) transhydrogenase alpha subunit.
     
 0.820
Your Current Organism:
Rhodopirellula islandica
NCBI taxonomy Id: 595434
Other names: DSM 24040, JCM 17612, R. islandica, Rhodopirellula sp. K833, strain K833
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