STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KLU05322.1Dihydrolipoamide succinyltransferase component (E2) of 2-oxoglutarate dehydrogenase complex; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (433 aa)    
Predicted Functional Partners:
KLU01493.1
2-oxoglutarate dehydrogenase E1 component.
 0.999
KLU02812.1
Dihydrolipoamide dehydrogenase of 2-oxoglutarate dehydrogenase.
 0.997
KLU04851.1
Dihydrolipoamide dehydrogenase of pyruvate dehydrogenase complex.
 0.996
sucC
Succinyl-CoA ligase [ADP-forming] beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
 
 0.990
sucD
Succinyl-CoA ligase [ADP-forming] alpha chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
  
 0.984
KLU06571.1
Malonyl CoA-acyl carrier protein transacylase.
  
 0.966
KLU07030.1
Glutamate synthase [NADPH] large chain.
     
 0.957
KLU03842.1
Malonyl CoA-acyl carrier protein transacylase.
   
 0.945
KLU05016.1
Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
  
 
 0.941
KLU01693.1
Two-component signal transduction.
    
 0.941
Your Current Organism:
Rhodopirellula islandica
NCBI taxonomy Id: 595434
Other names: DSM 24040, JCM 17612, R. islandica, Rhodopirellula sp. K833, strain K833
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