STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tola_0035PFAM: porin LamB type; KEGG: ypb:YPTS_3827 porin LamB type. (411 aa)    
Predicted Functional Partners:
Tola_0034
PFAM: Maltose operon periplasmic; KEGG: yen:YE3861 maltose regulon periplasmic protein.
 
  
 0.960
Tola_0037
Extracellular solute-binding protein family 1; Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Binds maltose and higher maltodextrins. Belongs to the bacterial solute-binding protein 1 family.
 
  
 0.914
secA
Preprotein translocase, SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. Belongs to the SecA family.
    
 
 0.880
Tola_0039
PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: vha:VIBHAR_05216 maltose transporter permease.
 
  
 0.865
malK-2
ABC transporter related; Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Maltooligosaccharide importer (TC 3.A.1.1.1) family.
 
  
 0.821
Tola_0038
PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: spe:Spro_4473 maltose transporter membrane protein.
 
  
 0.804
malT
ATP-dependent transcriptional regulator, MalT-like, LuxR family; Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto- oligosaccharides. Specifically binds to the promoter region of its target genes, recognizing a short DNA motif called the MalT box.
 
   
 0.786
Tola_0648
PFAM: alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; KEGG: ypi:YpsIP31758_4138 periplasmic alpha-amylase precursor.
 
  
 0.765
malK
ABC transporter related; Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Maltooligosaccharide importer (TC 3.A.1.1.1) family.
 
  
 0.719
btuB
TonB-dependent receptor; Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans- periplasmic membrane protein TonB; Belongs to the TonB-dependent receptor family. BtuB (TC 1.B.14.3.1) subfamily.
  
  
 0.682
Your Current Organism:
Tolumonas auensis
NCBI taxonomy Id: 595494
Other names: T. auensis DSM 9187, Tolumonas auensis DSM 9187, Tolumonas auensis TA 4, Tolumonas auensis str. DSM 9187, Tolumonas auensis strain DSM 9187
Server load: medium (44%) [HD]