STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tola_0216Diguanylate cyclase/phosphodiesterase with extracellular sensor; KEGG: sdn:Sden_0572 GGDEF domain-containing protein; TIGRFAM: diguanylate cyclase; PFAM: EAL domain protein; GGDEF domain containing protein; CHASE4 domain protein; histidine kinase HAMP region domain protein; SMART: EAL domain protein; GGDEF domain containing protein. (764 aa)    
Predicted Functional Partners:
Tola_2839
KEGG: dvl:Dvul_2249 diguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(s); TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: EAL domain protein; GGDEF domain containing protein; CHASE4 domain protein; PAS fold-4 domain protein; PAS fold domain protein; histidine kinase HAMP region domain protein; SMART: EAL domain protein; GGDEF domain containing protein.
 
 
0.778
Tola_1388
Hpt sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; Hpt domain protein; histidine kinase A domain protein; SMART: response regulator receiver; histidine kinase A domain protein; Hpt domain protein; ATP-binding region ATPase domain protein; KEGG: mno:Mnod_4585 multi-sensor hybrid histidine kinase.
  
 0.747
Tola_1953
Diguanylate cyclase with PAS/PAC and GAF sensors; KEGG: pfl:PFL_1403 sensory box-containing diguanylate cyclase, putative; TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: GGDEF domain containing protein; PAS fold-3 domain protein; GAF domain protein; PAS fold domain protein; PAS fold-4 domain protein; SMART: GGDEF domain containing protein; GAF domain protein; PAS domain containing protein.
 
 
0.725
Tola_1314
Diguanylate cyclase with PAS/PAC and GAF sensors; KEGG: eca:ECA3270 hypothetical protein; TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: GGDEF domain containing protein; PAS fold-3 domain protein; GAF domain protein; PAS fold domain protein; PAS fold-4 domain protein; SMART: GGDEF domain containing protein; PAC repeat-containing protein; GAF domain protein; PAS domain containing protein.
 
 
0.724
Tola_2079
KEGG: bph:Bphy_3794 diguanylate cyclase/phosphodiesterase with PAS/PAC and CHASE sensor(s); TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: GGDEF domain containing protein; CHASE domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: GGDEF domain containing protein; PAC repeat-containing protein; PAS domain containing protein.
 
 
0.724
Tola_0617
Multi-sensor hybrid histidine kinase; KEGG: aha:AHA_0905 aerobic respiration control sensor protein ArcB; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; Hpt domain protein; PAS fold-4 domain protein; PAS fold domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; Hpt domain protein; PAS domain containing protein.
 
 0.722
Tola_2087
PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; KEGG: azo:azo2200 HD-domain-containing protein.
  
 0.722
Tola_1998
KEGG: glo:Glov_1989 multi-sensor hybrid histidine kinase; TIGRFAM: diguanylate cyclase; hemerythrin-like metal-binding protein; PAS sensor protein; PFAM: GGDEF domain containing protein; PAS fold-3 domain protein; PAS fold domain protein; PAS fold-4 domain protein; Hemerythrin HHE cation binding domain protein; SMART: GGDEF domain containing protein; PAS domain containing protein.
 
 
0.671
Tola_2222
Diguanylate cyclase/phosphodiesterase; KEGG: aha:AHA_2484 GGDEF/eal domain-containing protein; TIGRFAM: diguanylate cyclase; PFAM: EAL domain protein; GGDEF domain containing protein; SMART: EAL domain protein; GGDEF domain containing protein.
 
 
0.663
Tola_1263
Diguanylate cyclase/phosphodiesterase with extracellular sensor; KEGG: asa:ASA_1673 GGDEF/EAL protein; TIGRFAM: diguanylate cyclase; PFAM: EAL domain protein; GGDEF domain containing protein; histidine kinase HAMP region domain protein; SMART: EAL domain protein; GGDEF domain containing protein.
 
 
0.661
Your Current Organism:
Tolumonas auensis
NCBI taxonomy Id: 595494
Other names: T. auensis DSM 9187, Tolumonas auensis DSM 9187, Tolumonas auensis TA 4, Tolumonas auensis str. DSM 9187, Tolumonas auensis strain DSM 9187
Server load: medium (58%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.