STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
macBABC transporter related; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. (659 aa)    
Predicted Functional Partners:
Tola_0294
TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: yen:YE1200 HlyD family secretion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 
 0.997
Tola_0292
TIGRFAM: RND efflux system, outer membrane lipoprotein, NodT family; PFAM: outer membrane efflux protein; KEGG: hch:HCH_01213 outer membrane protein.
 
 
 0.988
Tola_0354
TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: gme:Gmet_0809 secretion protein HlyD; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 
 0.967
Tola_1355
TIGRFAM: efflux transporter, RND family, MFP subunit; KEGG: lpf:lpl0882 hypothetical protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 
 0.960
Tola_2299
TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: dar:Daro_2957 secretion protein HlyD; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
  
 
 0.953
Tola_2568
TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: slo:Shew_2439 RND family efflux transporter MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
  
 
 0.953
Tola_2907
TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: asa:ASA_0024 membrane-fusion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
  
 
 0.953
Tola_2988
TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: psa:PST_3362 heavy metal RND efflux membrane fusion protein, CzcB family; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
  
 
 0.953
Tola_0352
TIGRFAM: RND efflux system, outer membrane lipoprotein, NodT family; PFAM: outer membrane efflux protein; KEGG: aha:AHA_2909 outer membrane protein OprM.
 
 
 0.904
Tola_2464
TIGRFAM: RND efflux system, outer membrane lipoprotein, NodT family; PFAM: outer membrane efflux protein; KEGG: pla:Plav_3444 RND efflux system outer membrane lipoprotein.
 
 
 0.901
Your Current Organism:
Tolumonas auensis
NCBI taxonomy Id: 595494
Other names: T. auensis DSM 9187, Tolumonas auensis DSM 9187, Tolumonas auensis TA 4, Tolumonas auensis str. DSM 9187, Tolumonas auensis strain DSM 9187
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