STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
btuBTonB-dependent receptor; Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans- periplasmic membrane protein TonB; Belongs to the TonB-dependent receptor family. BtuB (TC 1.B.14.3.1) subfamily. (617 aa)    
Predicted Functional Partners:
Tola_1802
TonB family protein; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.
 
 
 
 0.934
Tola_1133
PFAM: OmpA domain protein transmembrane region-containing protein; OmpA/MotB domain protein; KEGG: aha:AHA_1280 major outer membrane protein OmpAII; Belongs to the outer membrane OOP (TC 1.B.6) superfamily.
  
  
 0.722
Tola_0035
PFAM: porin LamB type; KEGG: ypb:YPTS_3827 porin LamB type.
  
  
 0.682
Tola_2868
PFAM: polysaccharide export protein; KEGG: eca:ECA1417 putative polysaccharide export protein.
  
  
 0.667
Tola_2127
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
 
   
 0.578
Tola_2396
PFAM: Cobyrinic acid ac-diamide synthase; KEGG: bpt:Bpet1290 hypothetical protein.
    
 
 0.568
Tola_3142
PFAM: Cobyrinic acid ac-diamide synthase; KEGG: aha:AHA_4271 Soj protein.
    
 
 0.568
Tola_0483
PFAM: porin Gram-negative type; KEGG: aha:AHA_0463 hypothetical protein.
   
 
 0.495
tolB
Tol-Pal system beta propeller repeat protein TolB; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
    
 
 0.481
Tola_0614
PFAM: periplasmic binding protein; KEGG: aha:AHA_1704 periplasmic binding protein.
 
  
 0.459
Your Current Organism:
Tolumonas auensis
NCBI taxonomy Id: 595494
Other names: T. auensis DSM 9187, Tolumonas auensis DSM 9187, Tolumonas auensis TA 4, Tolumonas auensis str. DSM 9187, Tolumonas auensis strain DSM 9187
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