STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cpdACalcineurin phosphoesterase domain protein; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. (273 aa)    
Predicted Functional Partners:
Tola_3126
PFAM: adenylate cyclase class-I; KEGG: aha:AHA_0470 adenylate cyclase; Belongs to the adenylyl cyclase class-1 family.
  
  
 0.971
Tola_2744
TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase; KEGG: aha:AHA_0819 MazG family protein.
  
  
  0.915
Tola_0807
PFAM: 5'-Nucleotidase domain protein; metallophosphoesterase; KEGG: ppr:PBPRB0897 5'-nucleotidase; Belongs to the 5'-nucleotidase family.
   
 
 0.912
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
     
 0.904
Tola_0491
PFAM: conserved hypothetical protein; KEGG: asa:ASA_3181 lysine decarboxylase family protein.
    
  0.903
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
  
 
  0.903
Tola_1065
TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 1; HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: spc:Sputcn32_3620 nucleotidase.
    
  0.901
Tola_2327
TIGRFAM: adenylosuccinate lyase; PFAM: Adenylosuccinate lyase domain protein; fumarate lyase; KEGG: asa:ASA_1389 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
     
  0.900
surE
Stationary-phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
     
  0.900
Tola_0395
PFAM: protein of unknown function UPF0227; KEGG: aha:AHA_3762 esterase YqiA.
  
  
 0.882
Your Current Organism:
Tolumonas auensis
NCBI taxonomy Id: 595494
Other names: T. auensis DSM 9187, Tolumonas auensis DSM 9187, Tolumonas auensis TA 4, Tolumonas auensis str. DSM 9187, Tolumonas auensis strain DSM 9187
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